公开(公告)号：US5069792A

公开(公告)日：1991-12-03

申请号：US551598

申请日：1990-07-10

申请人： Paul R. Prince ,  William D. Callaway

发明人： Paul R. Prince ,  William D. Callaway

IPC分类号： A61M1/02 ,  A61M1/26 ,  A61M1/34 ,  B01D61/22

CPC分类号： A61M1/34 ,  A61M1/262 ,  B01D61/22

摘要： An adaptive filter concentrate flow control system and method includes a filter system, a pumping system driving feed fluid, concentrate and filtrate flowing through the filter system and a flow control system controlling the pumping system to maintain optimum filtrate flow rates or minimum feed flow rates along a control surface in a three dimensional transmembrane pressure--feed fluid rate--filtrate flow rate space. Actual sensed operating point data is used to locate the control surface so as to assure an optimized filtrate flow rate or minimized feed flow rate at which reversible blocking of the membrane has begun to occur without irreversible blocking or plugging. The system is advantageously employed to control and maximize the flow of plasma in a plasmapheresis system or to minimize the rate at which blood is withdrawn from a donor and introduced into the system while achieving a fixed rate of plasma flow.

摘要翻译： 适应性过滤浓缩物流量控制系统和方法包括过滤系统，驱动进料流体的泵送系统，流过过滤系统的浓缩物和滤液以及控制泵送系统的流量控制系统，以保持最佳滤液流速或最小进料流速 三维跨膜压力进料流体速率 - 滤液流量空间中的控制表面。 实际检测到的工作点数据用于定位控制表面，以确保最佳滤液流速或最小化的进料流速，在此处开始膜的可逆阻塞而没有不可逆的阻塞或堵塞。 该系统有利地用于控制和最大化血浆置换系统中的血浆的流动，或者最小化血液从供体中取出并被引入系统中的速率，同时实现固定的血浆流速。