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1.发明授权Genes associated with mechanical stress, expression products therefrom, and uses thereof 失效与机械应力相关的基因，表达产物及其用途公开(公告)号：US07259253B2
公开(公告)日：2007-08-21
申请号：US10454351
申请日：2003-06-04
申请人： Paz Einat , Orit Segev , Rami Skaliter , Elena Feinstein , Alexander Faerman , Aviva Samach
发明人： Paz Einat , Orit Segev , Rami Skaliter , Elena Feinstein , Alexander Faerman , Aviva Samach
摘要： The disclosure relates to human and mechanical stress induced genes, in particular gene 608, and functional equivalents, probes therefor, tests to identify such genes, polypeptide expression products of such genes, antibodies to the polypeptides, uses for such genes, expression products and antibodies, e.g., in diagnosis (for instance risk determination), treatment, prevention, or control, of osteoporosis or fractures; and to diagnostic, treatment, prevention, or control methods or processes, as well as compositions therefor and methods or processes for making and using such compositions, and receptors therefor and methods or processes for obtaining and using such receptors.
摘要翻译： 本公开涉及人和机械应激诱导的基因，特别是基因608和功能等同物，其探针，鉴定这些基因的测试，这些基因的多肽表达产物，对多肽的抗体，用于这些基因，表达产物和抗体 ，例如骨质疏松症或骨折的诊断（例如风险确定），治疗，预防或控制; 以及诊断，治疗，预防或控制方法或过程，以及其组合物以及用于制备和使用这些组合物及其受体的方法或方法以及用于获得和使用此类受体的方法或方法。
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2.发明申请GENES ASSOCIATED WITH MECHANICAL STRESS, EXPRESSION PRODUCTS THEREFROM, AND USES THEREOF 审中-公开与机械应力相关的基因，其表达产物及其用途公开(公告)号：US20090258021A1
公开(公告)日：2009-10-15
申请号：US11841827
申请日：2007-08-20
申请人： Paz EINAT , Orit Segev , Rami Skaliter , Elena Feinstein , Alexander Faerman , Aviva Samach
发明人： Paz EINAT , Orit Segev , Rami Skaliter , Elena Feinstein , Alexander Faerman , Aviva Samach
IPC分类号： A61K39/395 , C07K14/00 , C07K16/18 , A61P35/00
摘要： The disclosure relates to human and mechanical stress induced genes, in particular gene 608, and functional equivalents, probes therefor, tests to identify such genes, polypeptide expression products of such genes, antibodies to the polypeptides, uses for such genes, expression products and antibodies, e.g., in diagnosis (for instance risk determination), treatment, prevention, or control, of osteoporosis or fractures; and to diagnostic, treatment, prevention, or control methods or processes, as well as compositions therefor and methods or processes for making and using such compositions, and receptors therefor and methods or processes for obtaining and using such receptors.
摘要翻译： 本公开涉及人和机械应激诱导的基因，特别是基因608和功能等同物，其探针，鉴定这些基因的测试，这些基因的多肽表达产物，对多肽的抗体，用于这些基因，表达产物和抗体 ，例如骨质疏松症或骨折的诊断（例如风险确定），治疗，预防或控制; 以及诊断，治疗，预防或控制方法或过程，以及其组合物以及用于制备和使用这些组合物及其受体的方法或方法以及用于获得和使用这些受体的方法或方法。
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