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公开(公告)号：US11456058B2
公开(公告)日：2022-09-27
申请号：US17746669
申请日：2022-05-17
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US20160019341A1
公开(公告)日：2016-01-21
申请号：US14871020
申请日：2015-09-30
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
IPC: G06F19/22
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US20210193260A1
公开(公告)日：2021-06-24
申请号：US16952507
申请日：2020-11-19
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US09727692B2
公开(公告)日：2017-08-08
申请号：US14871020
申请日：2015-09-30
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US20240257913A1
公开(公告)日：2024-08-01
申请号：US18431138
申请日：2024-02-02
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
CPC classification number: G16B30/10 , G06N3/126 , G16B20/00 , G16B20/20 , G16B30/00 , G16H50/00 , C12Q1/68
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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Patent Agency Ranking
公开(公告)号：US11935625B2
公开(公告)日：2024-03-19
申请号：US16952507
申请日：2020-11-19
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
CPC classification number: G16B30/10 , G06N3/126 , G16B20/00 , G16B20/20 , G16B30/00 , G16H50/00 , C12Q1/68
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US10032000B1
公开(公告)日：2018-07-24
申请号：US15639610
申请日：2017-06-30
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US20220392577A1
公开(公告)日：2022-12-08
申请号：US17817581
申请日：2022-08-04
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US20220277810A1
公开(公告)日：2022-09-01
申请号：US17746669
申请日：2022-05-17
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
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公开(公告)号：US09183496B2
公开(公告)日：2015-11-10
申请号：US14474034
申请日：2014-08-29
Applicant: Personalis, Inc.
Inventor： Jason Harris , Mark R. Pratt , John West , Richard Chen , Ming Li
Abstract: A computer-implemented method for processing and/or analyzing nucleic acid sequencing data comprises receiving a first data input and a second data input. The first data input comprises untargeted sequencing data generated from a first nucleic acid sample obtained from a subject. The second data input comprises target-specific sequencing data generated from a second nucleic acid sample obtained from the subject. Next, with the aid of a computer processor, the first data input and the second data input are combined to produce a combined data set. Next, an output derived from the combined data set is generated. The output is indicative of the presence or absence of one or more polymorphisms of the first nucleic acid sample and/or the second nucleic acid sample.
Abstract translation: 用于处理和/或分析核酸测序数据的计算机实现的方法包括接收第一数据输入和第二数据输入。 第一数据输入包括从从受试者获得的第一核酸样品产生的非靶向测序数据。 第二数据输入包括从从受试者获得的第二核酸样品产生的靶特异性测序数据。 接下来，借助于计算机处理器，组合第一数据输入和第二数据输入以产生组合数据集。 接下来，生成从组合数据集导出的输出。 输出指示第一核酸样品和/或第二核酸样品的一个或多个多态性的存在或不存在。
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