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公开(公告)号:US20050037337A1
公开(公告)日:2005-02-17
申请号:US10630880
申请日:2003-07-30
申请人: Peter Ertl , Gerald Gough , Christopher Ring , Vanita Parmar , Sarah Walcott
发明人: Peter Ertl , Gerald Gough , Christopher Ring , Vanita Parmar , Sarah Walcott
CPC分类号: C07K14/005 , A61K39/00 , A61K2039/53 , C07K2319/00 , C12N15/67 , C12N2710/14143 , C12N2710/20022 , C12N2710/24143
摘要: The present invention relates to methods and compositions useful in the treatment and prevention of human papilloma virus infections and the symptoms and diseases associated therewith. More particularly, the invention relates to polynucleotide sequences which encode human papilloma virus (HPV) amino acid amino acid sequences, wherein the codon usage pattern of the polynucleotide sequences resemble those of highly expressed mammalian genes.
摘要翻译: 本发明涉及可用于治疗和预防人乳头状瘤病毒感染的方法和组合物以及与其相关的症状和疾病。 更具体地,本发明涉及编码人乳头瘤病毒(HPV)氨基酸氨基酸序列的多核苷酸序列,其中多核苷酸序列的密码子使用模式类似于高度表达的哺乳动物基因的密码子使用模式。