公开(公告)号：US20140045790A1

公开(公告)日：2014-02-13

申请号：US14053924

申请日：2013-10-15

Applicant: Pfizer Inc.

Inventor： Martin Youngjin Pettersson ,  Douglas Scott Johnson ,  Chakrapani Subramanyam ,  Christopher John O'Donnell ,  Christopher William am Ende ,  Benjamin Adam Fish ,  Michael Eric Green ,  Patrick Bradley Mullins ,  Cory Michael Stiff ,  Tuan Phong Tran ,  Thayalan Navaratnam

IPC: C07D471/04 ,  C07D401/04 ,  C07F7/08 ,  C07D491/048 ,  A61K31/695 ,  A61K31/4985 ,  A61K45/06

CPC classification number: C07D471/04 ,  A61K31/4985 ,  A61K31/695 ,  A61K45/06 ,  C07D401/04 ,  C07D491/048 ,  C07F7/0812

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract translation: 公开了化合物的化合物和药学上可接受的盐，其中所述化合物具有如本文所定义的式I的结构。 还公开了相应的药物组合物，治疗方法，合成方法和中间体。

公开(公告)号：US09067934B2

公开(公告)日：2015-06-30

申请号：US14053924

申请日：2013-10-15

Applicant: Pfizer Inc.

Inventor： Martin Youngjin Pettersson ,  Douglas Scott Johnson ,  Chakrapani Subramanyam ,  Christopher John O'Donnell ,  Christopher William am Ende ,  Benjamin Adam Fish ,  Michael Eric Green ,  Patrick Bradley Mullins ,  Cory Michael Stiff ,  Tuan Phong Tran ,  Thayalan Navaratnam

IPC: C07D471/04 ,  C07D401/04 ,  A61K31/4985 ,  A61K31/695 ,  A61K45/06 ,  C07D491/048 ,  C07F7/08

CPC classification number: C07D471/04 ,  A61K31/4985 ,  A61K31/695 ,  A61K45/06 ,  C07D401/04 ,  C07D491/048 ,  C07F7/0812

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract translation: 公开了化合物的化合物和药学上可接受的盐，其中所述化合物具有如本文所定义的式I的结构。 还公开了相应的药物组合物，治疗方法，合成方法和中间体。