公开(公告)号：US20240132483A1

公开(公告)日：2024-04-25

申请号：US18513752

申请日：2023-11-20

Applicant: Pfizer Inc.

Inventor： Gary Erik Aspnes ,  Scott W. Bagley ,  Edward L. Conn ,  John M. Curto ,  David J. Edmonds ,  Mark E. Flanagan ,  Kentaro Futatsugi ,  David A. Griffith ,  Kim Huard ,  Chris Limberakis ,  Alan M. Mathiowetz ,  David W. Piotrowski ,  Roger B. Ruggeri

IPC: C07D405/14 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D471/04

CPC classification number: C07D405/14 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D471/04

Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

公开(公告)号：US11858916B2

公开(公告)日：2024-01-02

申请号：US17251929

申请日：2019-06-13

Applicant: Pfizer Inc.

Inventor： Gary Erik Aspnes ,  Scott W. Bagley ,  Edward L. Conn ,  John M. Curto ,  David J. Edmonds ,  Mark E. Flanagan ,  Kentaro Futatsugi ,  David A. Griffith ,  Kim Huard ,  Chris Limberakis ,  Alan M. Mathiowetz ,  David W. Piotrowski ,  Roger B. Ruggeri

IPC: C07D405/14 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D471/04

CPC classification number: C07D405/14 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D471/04

Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

公开(公告)号：US20210332034A1

公开(公告)日：2021-10-28

申请号：US17251929

申请日：2019-06-13

Applicant: Pfizer Inc.

Inventor： Gary Erik Aspnes ,  Scott W. Bagley ,  Edward L. Conn ,  John M. Curto ,  David J. Edmonds ,  Mark E. Flanagan ,  Kentaro Futatsugi ,  David A. Griffith ,  Kim Huard ,  Chris Limberakis ,  Alan M. Mathiowetz ,  David W. Piotrowski ,  Roger B. Ruggeri

IPC: C07D405/14 ,  C07D471/04 ,  C07D401/14 ,  C07D413/14 ,  C07D403/14

Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.