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公开(公告)号:US09545405B2
公开(公告)日:2017-01-17
申请号:US14691606
申请日:2015-04-21
申请人: Pfizer Inc.
发明人: Matthew Frank Brown , Ashley Edward Fenwick , Mark Edward Flanagan , Andrea Gonzales , Timothy Allan Johnson , Neelu Kaila , Mark J. Mitton-Fry , Joseph Walter Strohbach , Ruth E. TenBrink , John David Trzupek , Rayomand Jal Unwalla , Michael L. Vazquez , Mihir D. Parikh
IPC分类号: A01N43/90 , A61K31/519 , C07D487/00 , C07D487/04 , C07D519/00 , A61K31/5386 , C07D207/18
CPC分类号: A61K31/519 , A61K31/5386 , C07D207/18 , C07D487/04 , C07D519/00
摘要: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
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公开(公告)号:US20150246048A1
公开(公告)日:2015-09-03
申请号:US14715046
申请日:2015-05-18
申请人: Pfizer Inc.
发明人: Matthew Frank Brown , Ashley Edward Fenwick , Mark Edward Flanagan , Andrea Gonzales , Timothy Allan Johnson , Neelu Kaila , Mark J. Mitton-Fry , Joseph Walter Strohbach , Ruth E. TenBrink , John David Trzupek , Rayomand Jal Unwalla , Michael L. Vazquez , Mihir D. Parikh
IPC分类号: A61K31/519 , A61K31/5386
CPC分类号: A61K31/519 , A61K31/5386 , C07D207/18 , C07D487/04 , C07D519/00
摘要: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
摘要翻译: 本文描述的是吡咯并[2,3-d]嘧啶衍生物,它们用作Janus Kinase(JAK)抑制剂,以及含有它们的药物组合物。
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公开(公告)号:US09035074B2
公开(公告)日:2015-05-19
申请号:US14183946
申请日:2014-02-19
申请人: Pfizer Inc.
发明人: Matthew Frank Brown , Ashley Edward Fenwick , Mark Edward Flanagan , Andrea Gonzales , Timothy Allan Johnson , Neelu Kaila , Mark J. Mitton-Fry , Joseph Walter Strohbach , Ruth E. TenBrink , John David Trzupek , Rayomand Jal Unwalla , Michael L. Vazquez , Mihir D. Parikh
IPC分类号: C07D207/18 , C07D487/04 , C07D519/00
CPC分类号: A61K31/519 , A61K31/5386 , C07D207/18 , C07D487/04 , C07D519/00
摘要: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
摘要翻译: 本文描述的是吡咯并[2,3-d]嘧啶衍生物,它们用作Janus Kinase(JAK)抑制剂,以及含有它们的药物组合物。
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公开(公告)号:US20140243312A1
公开(公告)日:2014-08-28
申请号:US14183946
申请日:2014-02-19
申请人: Pfizer Inc.
发明人: Matthew Frank Brown , Ashley Edward Fenwick , Mark Edward Flanagan , Andrea Gonzales , Timothy Allan Johnson , Neelu Kaila , Mark J. Mitton-Fry , Joseph Walter Strohbach , Ruth E. TenBrink , John David Trzupek , Rayomand Jal Unwalla , Michael L. Vazquez
IPC分类号: C07D487/04
CPC分类号: A61K31/519 , A61K31/5386 , C07D207/18 , C07D487/04 , C07D519/00
摘要: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
摘要翻译: 本文描述的是吡咯并[2,3-d]嘧啶衍生物,它们用作Janus Kinase(JAK)抑制剂,以及含有它们的药物组合物。
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公开(公告)号:US09549929B2
公开(公告)日:2017-01-24
申请号:US14715046
申请日:2015-05-18
申请人: Pfizer Inc.
发明人: Matthew Frank Brown , Ashley Edward Fenwick , Mark Edward Flanagan , Andrea Gonzales , Timothy Allan Johnson , Neelu Kaila , Mark J. Mitton-Fry , Joseph Walter Strohbach , Ruth E. TenBrink , John David Trzupek , Rayomand Jal Unwalla , Michael L. Vazquez , Mihir D. Parikh
IPC分类号: A61K31/519 , C07D487/04 , C07D519/00 , A61K31/5386 , C07D207/18
CPC分类号: A61K31/519 , A61K31/5386 , C07D207/18 , C07D487/04 , C07D519/00
摘要: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
摘要翻译: 本文描述的是吡咯并[2,3-d]嘧啶衍生物,它们用作Janus Kinase(JAK)抑制剂,以及含有它们的药物组合物。
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公开(公告)号:US20150225408A1
公开(公告)日:2015-08-13
申请号:US14691606
申请日:2015-04-21
申请人: Pfizer Inc.
发明人: Matthew Frank Brown , Ashley Edward Fenwick , Mark Edward Flanagan , Andrea Gonzales , Timothy Allan Johnson , Neelu Kaila , Mark J. Mitton-Fry , Joseph Walter Strohbach , Ruth E. TenBrink , John David Trzupek , Rayomand Jal Unwalla , Michael L. Vazquez , Mihir D. Parikh
IPC分类号: C07D487/04 , C07D519/00
CPC分类号: A61K31/519 , A61K31/5386 , C07D207/18 , C07D487/04 , C07D519/00
摘要: Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
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公开(公告)号:US20150148326A1
公开(公告)日:2015-05-28
申请号:US14608826
申请日:2015-01-29
申请人: Pfizer Inc.
发明人: Matthew F. Brown , Mark J. Mitton-Fry , Seungil Han , Manjinder Lall , Mark Plummer , Hud Lawrence Risley , Veerabahu Shanmugasundaram , Jeremy Starr
IPC分类号: C07D417/14
CPC分类号: C07D417/14 , C07D205/08
摘要: The present invention is directed to a new class of monobactam derivatives and their use for treating bacterial infections.
摘要翻译: 本发明涉及一类新颖的单链内酰胺衍生物及其用于治疗细菌感染的用途。
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公开(公告)号:US20130252935A1
公开(公告)日:2013-09-26
申请号:US13778670
申请日:2013-02-27
申请人: PFIZER INC.
发明人: Matthew F. Brown , Mark J. Mitton-Fry , Seungil Han , Manjinder Lall , Mark Plummer , Hud Lawrence Risley , Veerabahu Shanmugasundaram , Jeremy Starr
IPC分类号: C07D205/08
CPC分类号: C07D417/14 , C07D205/08
摘要: The present invention is directed to a new class of monobactam derivatives and their use for treating bacterial infections.
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