公开(公告)号：US11702474B2

公开(公告)日：2023-07-18

申请号：US17120935

申请日：2020-12-14

Applicant: Pfizer Inc.

Inventor： Javier Fernando Chaparro Riggers ,  Shih-Hsun Chen ,  Sheng Ding ,  Pawel Kamil Dominik ,  Shahram Salek-Ardakani ,  Jessica Lynn Stanfield ,  Thomas John Van Blarcom

IPC: C07K16/28 ,  A61P35/00 ,  A61K39/00

CPC classification number: C07K16/2827 ,  A61P35/00 ,  C07K16/2803 ,  A61K2039/505 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/52 ,  C07K2317/56 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: Antibodies that specifically bind to CD47 and antibodies that specifically bind to PD-L1 are provided, as well as CD47/PD-L1 bispecific antibodies. Also provided are uses of these antibodies, and related compositions and methods.