公开(公告)号：US20230340530A1

公开(公告)日：2023-10-26

申请号：US18041447

申请日：2021-08-27

Applicant: Pfizer Inc.

Inventor： Timothy Leyden Foley ,  Christopher John Helal

IPC: C12N15/86 ,  C12N15/113

CPC classification number: C12N15/86 ,  C12N15/113 ,  C12N2310/11 ,  C12N2320/51 ,  C12N2320/52 ,  C12N2770/24243

Abstract: The present invention provides methods of protecting ribonucleic acid (RNA) from degradation under certain conditions by contacting the RNA with compounds that contain at least one boron atom. The present invention also provides compositions comprising such compounds and RNA.