公开(公告)号：US11958016B2

公开(公告)日：2024-04-16

申请号：US16456778

申请日：2019-06-28

申请人： Pierce Biotechnology, Inc. ,  Life Technologies Corporation

发明人： Kay Opperman ,  Barbara Kaboord ,  Aaron McBride ,  Greg Nagy ,  Sandro Klein ,  Joanna Geddes

IPC分类号： A61M1/16 ,  B01D61/24 ,  B01D63/08

CPC分类号： B01D61/243 ,  A61M1/1619 ,  A61M1/1692 ,  B01D63/08 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/50

摘要： Dialysis devices include a frame defined by a plurality of sidewalls that are impermeable to a sample being dialyzed, a pair of dialysis membranes that are each associated with an opposing face of the plurality of sidewalls such that the plurality of sidewalls and the pair of dialysis membranes define a sample chamber, an outer shell surrounding at least a portion of the pair of dialysis membranes, and a cap selectively associated with the sample chamber. The cap can be selectively associated with the sample chamber via an attachment mechanism that is configured to provide aural and/or haptic feedback when the cap forms a tight association with the sample chamber. The cap can be a sensor cap having one or more probes for measuring at least one property of fluid inside and/or outside the sample chamber and a transmitter for transmitting data captured at the probe(s) to a destination device.

公开(公告)号：US20200000992A1

公开(公告)日：2020-01-02

申请号：US16456778

申请日：2019-06-28

申请人： Pierce Biotechnology, Inc. ,  Life Technologies Corporation

发明人： Kay Opperman ,  Barbara Kaboord ,  Aaron McBride ,  Greg Nagy ,  Sandro Klein ,  Joanna Geddes

IPC分类号： A61M1/16

摘要： Dialysis devices include a frame defined by a plurality of sidewalls that are impermeable to a sample being dialyzed, a pair of dialysis membranes that are each associated with an opposing face of the plurality of sidewalls such that the plurality of sidewalls and the pair of dialysis membranes define a sample chamber, an outer shell surrounding at least a portion of the pair of dialysis membranes, and a cap selectively associated with the sample chamber. The cap can be selectively associated with the sample chamber via an attachment mechanism that is configured to provide aural and/or haptic feedback when the cap forms a tight association with the sample chamber. The cap can be a sensor cap having one or more probes for measuring at least one property of fluid inside and/or outside the sample chamber and a transmitter for transmitting data captured at the probe(s) to a destination device.

公开(公告)号：US20240252988A1

公开(公告)日：2024-08-01

申请号：US18602164

申请日：2024-03-12

申请人： Pierce Biotechnology, Inc. ,  Life Technologies Corporation

发明人： Kay Opperman ,  Barbara Kaboord ,  Aaron McBride ,  Greg Nagy ,  Sandro Klein ,  Joanna Geddes

IPC分类号： B01D61/24 ,  A61M1/16 ,  B01D63/08

CPC分类号： B01D61/243 ,  A61M1/1619 ,  A61M1/1692 ,  B01D63/08 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/50

摘要： Dialysis devices include a frame defined by a plurality of sidewalls that are impermeable to a sample being dialyzed, a pair of dialysis membranes that are each associated with an opposing face of the plurality of sidewalls such that the plurality of sidewalls and the pair of dialysis membranes define a sample chamber, an outer shell surrounding at least a portion of the pair of dialysis membranes, and a cap selectively associated with the sample chamber. The cap can be selectively associated with the sample chamber via an attachment mechanism that is configured to provide aural and/or haptic feedback when the cap forms a tight association with the sample chamber. The cap can be a sensor cap having one or more probes for measuring at least one property of fluid inside and/or outside the sample chamber and a transmitter for transmitting data captured at the probe(s) to a destination device.

公开(公告)号：US12123814B1

公开(公告)日：2024-10-22

申请号：US16900019

申请日：2020-06-12

申请人： Pierce Biotechnology, Inc.

发明人： Barbara Kaboord ,  Joanna Geddes ,  Christopher Wojewodzki ,  Kay Opperman ,  Scott Meier

IPC分类号： C07K1/14 ,  C07K14/705 ,  C07K14/72 ,  G01N1/40 ,  C07H3/04 ,  C07J9/00 ,  C07J41/00

CPC分类号： G01N1/4044 ,  C07K1/145 ,  C07K14/705 ,  C07K14/723 ,  C07H3/04 ,  C07J9/00 ,  C07J41/0033 ,  G01N2001/4061

摘要： Formulations for extraction and stabilization of G-Protein Coupled Receptors (GPCRs), kits and methods for their use for extracting GPCRs from biological specimens (e.g., cells and tissues), and methods for making such formulations in bulk scale are described. GPCRs extracted from cells and tissues using the described formulations remain in a functional, solubilized form over extended time periods.