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公开(公告)号：US11802289B2
公开(公告)日：2023-10-31
申请号：US16635402
申请日：2018-08-02
Applicant: PlantForm Corporation
Inventor： Kiva Ferraro , Michael Marit , Michael D. McLean
CPC classification number: C12N15/8218 , C07K16/32 , C12N15/8258 , C07K2317/13 , C07K2317/24
Abstract: A plant or plant cell with reduced endogenous AGO1 and AGO4 expression compared to a wild-type plant or plant cell is provided. In one embodiment, the plant or plant cell further comprises a nucleic acid sequence encoding a recombinant protein and the plant or plant cell has increased expression of the recombinant protein compared to a wild-type plant or plant cell comprising the nucleic acid sequence. Methods of reducing aglycosylation of recombinant protein produced in plants are also provided.
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