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公开(公告)号：US11878968B2
公开(公告)日：2024-01-23
申请号：US18052462
申请日：2022-11-03
Applicant: Plexium, Inc.
Inventor： Pengyu Yang , Simon Bailey
IPC: C07D401/14 , A61P35/00
CPC classification number: C07D401/14
Abstract: Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2). The compounds are of formula I:
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公开(公告)号：US11807620B2
公开(公告)日：2023-11-07
申请号：US17180644
申请日：2021-02-19
Applicant: PLEXIUM, INC.
Inventor： Pengyu Yang , Mark Wilson , Mihai Azimioara
IPC: C07D401/04 , C07D401/14 , C07D487/04 , C07D498/08 , C07D498/18 , C07D413/14
CPC classification number: C07D401/04 , C07D401/14 , C07D413/14 , C07D487/04 , C07D498/08 , C07D498/18
Abstract: Disclosed are substituted quinazolinone compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions to treat diseases, disorders, or conditions such as those relating to unregulated protein function and/or levels.
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公开(公告)号：US11998919B2
公开(公告)日：2024-06-04
申请号：US17699001
申请日：2022-03-18
Applicant: Plexium, Inc.
Inventor： Yi Zhang , Jesse Lu , Alex Price , Pengyu Yang , Kandaswamy Vijayan
CPC classification number: B01L3/5085 , C12M23/12 , B01L2200/0668 , B01L2200/12 , B01L2300/0851 , B01L2300/0858 , B01L2300/0864 , B01L2300/0893 , B01L2300/165
Abstract: Disclosed is an assay device comprising a high density of wells aligned thereon.
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Patent Agency Ranking
公开(公告)号：US20230265071A1
公开(公告)日：2023-08-24
申请号：US18052462
申请日：2022-11-03
Applicant: Plexium, Inc.
Inventor： Pengyu Yang , Simon Bailey
IPC: C07D401/14
CPC classification number: C07D401/14
Abstract: Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2). The compounds are of formula I:
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公开(公告)号：US20210269413A1
公开(公告)日：2021-09-02
申请号：US17180644
申请日：2021-02-19
Applicant: PLEXIUM, INC.
Inventor： Pengyu Yang , Mark Wilson , Mihai Azimioara
IPC: C07D401/04 , C07D401/14 , C07D487/04 , C07D498/18 , C07D413/14
Abstract: Disclosed are substituted quinazolinone compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions to treat diseases, disorders, or conditions such as those relating to unregulated protein function and/or levels.
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公开(公告)号：US20240246935A1
公开(公告)日：2024-07-25
申请号：US18496709
申请日：2023-10-27
Applicant: Plexium, Inc.
Inventor： Pengyu Yang , Simon Bailey
IPC: C07D401/14
CPC classification number: C07D401/14
Abstract: Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2). The compounds are of formula I:
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公开(公告)号：US20220203357A1
公开(公告)日：2022-06-30
申请号：US17699001
申请日：2022-03-18
Applicant: Plexium, Inc.
Inventor： Yi Zhang , Jesse Lu , Alex Price , Pengyu Yang , Kandaswamy Vijayan
Abstract: Disclosed is an assay device comprising a high density of wells aligned thereon.
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公开(公告)号：US11305288B2
公开(公告)日：2022-04-19
申请号：US16774862
申请日：2020-01-28
Applicant: Plexium, Inc.
Inventor： Yi Zhang , Jesse Lu , Alex Price , Pengyu Yang , Kandaswamy Vijayan
Abstract: Disclosed is an assay device comprising a high density of wells aligned thereon.
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