公开(公告)号：US11536724B2

公开(公告)日：2022-12-27

申请号：US16065663

申请日：2016-12-23

申请人： Polyquant GmbH ,  COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS ,  LUXEMBOURG INSTITUTE OF HEALTH ,  INSTITUT CURIE ,  ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS ,  FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III, CNIO

发明人： Jerome Garin ,  Christophe Masselon ,  Antonia Vlahou ,  Manousos Makrydakis ,  Ieronimos Zoidakis ,  Bruno Domon ,  Elodie Duriez ,  Aurelie Kamoun ,  Francois Radvanyi ,  Yves Allory ,  Nuria Malats Riera ,  Mirari Marquez Cid ,  Magali Court

IPC分类号： G01N31/00 ,  G01N33/53 ,  G01N33/68 ,  C07K7/08 ,  G01N33/574 ,  C07K14/54 ,  C07K16/30

摘要： The invention relates to a collection of signature peptides representing at least 10 proteins for use in cancer diagnosis and/or prognosis, to an artificial protein comprising signature peptides representing at least 10 proteins and to a nucleic acid construct encoding for such an artificial protein. The invention further relates to a collection of at least 10 proteins for use in cancer diagnosis and/or prognosis. Additionally, the invention relates to a method for cancer diagnosis and/or prognosis comprising the step of analyzing at least 10 proteins in a urine sample of a subject. Finally, the invention relates to an immunoassay product comprising antibodies for detecting at least 10 proteins.