公开(公告)号：US20240140836A1

公开(公告)日：2024-05-02

申请号：US17768734

申请日：2020-09-30

Applicant: President and Fellows of Harvard College

Inventor： Elizabeth Calamari ,  Richard Novak ,  Manuel Ramses Martinez Flores ,  Alexandre L.M. Dinis ,  Robert Cunningham ,  Olivier Henry ,  Donald E. Ingber ,  Jeremy J. Papadopoulos

IPC: C02F1/48

CPC classification number: C02F1/48 ,  C02F2301/028 ,  C02F2303/04

Abstract: Microfluidic devices for sterilizing fluids using pulsed electric fields are disclosed. In some embodiments, a device may include first and second electrode layers and a spacer layer positioned between the electrode layers. The spacer layer may define one or more fluid channels extending between the electrode layers. A power supply may be coupled to the electrode layers and configured to supply voltage pulses to the electrode layers to generate electric field pulses within the fluid channels. In some embodiments, the electrode layers may be textured such that the electric fields generated in the fluid channels are non-uniform.