公开(公告)号：US20070093743A1

公开(公告)日：2007-04-26

申请号：US11535608

申请日：2006-09-27

申请人： Preston Keusch ,  Vilambi Reddy ,  Ashutosh Sharma ,  George Baskinger

发明人： Preston Keusch ,  Vilambi Reddy ,  Ashutosh Sharma ,  George Baskinger

IPC分类号： A61N1/30

CPC分类号： A61N1/30 ,  A61N1/0436 ,  A61N1/044 ,  A61N1/0448

摘要： An electrically assisted transdermal drug delivery system for highly effective electrotransport of an anesthetic and a vasoconstrictor producing clinically acceptable depth and duration of dermal anesthesia at a treatment site. In certain embodiments, the anesthetic comprises lidocaine and the vasoconstrictor comprises epinephrine.

摘要翻译： 用于麻醉剂和血管收缩剂的高效电运输的电辅助透皮药物递送系统，其在治疗部位产生临床可接受的皮肤麻醉深度和持续时间。 在某些实施方案中，麻醉剂包含利多卡因，血管收缩剂包含肾上腺素。

公开(公告)号：US20070078434A1

公开(公告)日：2007-04-05

申请号：US11537182

申请日：2006-09-29

申请人： Preston Keusch ,  Vilambi Reddy ,  Richard Greene ,  George Baskinger ,  Ashutosh Sharma

发明人： Preston Keusch ,  Vilambi Reddy ,  Richard Greene ,  George Baskinger ,  Ashutosh Sharma

IPC分类号： A61M31/00

CPC分类号： A61N1/30 ,  A61N1/044 ,  A61N1/0448

摘要： The use of an iontophoresis electrode assembly for delivery of a drug formulation is described. The drug formulation includes an anaesthetic and a vasoconstrictor. It is administered to a patient prior to a procedure to produce clinically acceptable depth and duration of dermal anaesthesia at the portion of skin to subject to a painful procedure or to reduce or eliminate pain. The procedure is one selected from the group consisting of venipuncture, IV cannulation, needle aspirations, body piercings, blood donations, electrolysis, tattoo removal, tattoo application, injections, dermabrasion, skin peeling, high velocity particle ablation, pace maker implantation, pace maker replacement, epidural puncture, lumbar puncture, regional nerve blocks, skin harvesting, small skin incisions, skin biopsies, circumcisions or excisions. The iontophoresis electrode assembly may also be used to reduce or temporarily eliminate neuropathic pain.

摘要翻译： 描述了用于递送药物制剂的离子电渗电极组件的使用。 药物制剂包括麻醉剂和血管收缩剂。 在手术部分之前产生临床上可接受的皮肤麻醉深度和持续时间的患者施用于患者，以忍受痛苦的过程或减轻或消除疼痛。 该方法选自静脉穿刺，IV插管，针吸，身体穿刺，献血，电解，纹身去除，纹身应用，注射，皮肤磨皮，皮肤剥离，高速颗粒消融，起搏器植入，起搏器 替代，硬膜外穿刺，腰椎穿刺，局部神经阻滞，皮肤收获，小皮肤切口，皮肤活检，切割或切除。 离子电渗电极组件也可用于减少或暂时消除神经性疼痛。