公开(公告)号：US11564963B2

公开(公告)日：2023-01-31

申请号：US16882429

申请日：2020-05-22

申请人： Progeneron, LLC

发明人： David Scharp ,  Mukhtar Siddiqui ,  Jennifer Aguas Hurtikant ,  David Bondurant ,  Brian Haight

IPC分类号： A61K36/23 ,  A61Q19/08 ,  A61K9/107 ,  A61K31/015 ,  A61K47/42 ,  A61K36/28 ,  A61K31/25 ,  A61K36/185 ,  A61K31/201 ,  A61K31/05 ,  A61K31/455 ,  A61K47/14 ,  A61K36/886 ,  A61K47/26 ,  A61K33/06 ,  A61K8/9794 ,  A61K8/9789 ,  A61K8/31 ,  A61K9/00

摘要： Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

公开(公告)号：US20200281998A1

公开(公告)日：2020-09-10

申请号：US16882429

申请日：2020-05-22

申请人： Progeneron, LLC

发明人： David Scharp ,  Mukhtar Siddiqui ,  Jennifer Aguas Hurtikant ,  David Bondurant ,  Brian Haight

IPC分类号： A61K36/23 ,  A61K9/00 ,  A61K9/107 ,  A61K31/015 ,  A61K47/42 ,  A61K36/28 ,  A61K31/25 ,  A61K36/185 ,  A61K31/201 ,  A61K31/05 ,  A61K31/455 ,  A61K47/14 ,  A61K36/886 ,  A61K47/26 ,  A61K33/06 ,  A61K8/9794 ,  A61K8/9789 ,  A61K8/31 ,  A61Q19/08

摘要： Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.