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公开(公告)号：US20230301960A1
公开(公告)日：2023-09-28
申请号：US18055778
申请日：2022-11-15
申请人： QBIOTICS PTY LTD
IPC分类号： A61K31/336 , A01N43/20 , A01N43/90 , A01N45/00 , C07D301/32 , C07D303/14 , C07D303/32 , C07D493/04 , A01N53/00 , C07D303/44 , C07D303/17 , A61K9/00 , A61K9/06 , A61K47/10
CPC分类号： A61K31/336 , A01N43/20 , A01N43/90 , A01N45/00 , A01N53/00 , A61K9/0014 , A61K9/0019 , A61K9/06 , A61K47/10 , C07D301/32 , C07D303/14 , C07D303/17 , C07D303/32 , C07D303/44 , C07D493/04
摘要： The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment
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公开(公告)号：US20200179325A1
公开(公告)日：2020-06-11
申请号：US16702296
申请日：2019-12-03
申请人： QBIOTICS PTY LTD
IPC分类号： A61K31/336 , A61K47/10 , A61K9/06 , A61K9/00 , C07D303/17 , C07D303/44 , A01N53/00 , C07D493/04 , C07D303/32 , C07D303/14 , C07D301/32 , A01N45/00 , A01N43/90 , A01N43/20
摘要： The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment
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公开(公告)号：US20200030279A1
公开(公告)日：2020-01-30
申请号：US16496333
申请日：2018-03-23
申请人： QBIOTICS PTY LTD
发明人： Paul Warren Reddell , Jason Kingsley Cullen , Glen Mathew Boyle , Peter Gordon Parsons , Victoria Anne Gordon
IPC分类号： A61K31/336 , A61P35/00 , A61K9/00 , A61K39/395
摘要： The present invention relates to a combination therapy for tumours comprising the administration of an epoxytigliane compound and an immune checkpoint inhibitor. In particular embodiments, there is a method of treating a tumour and/or treating or preventing one or more bystander tumours with the therapy. Pharmaceutical compositions and kits containing epoxytigliane compounds and immune checkpoint inhibitors are also described.
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公开(公告)号：US10980769B2
公开(公告)日：2021-04-20
申请号：US16702296
申请日：2019-12-03
申请人： QBIOTICS PTY LTD
IPC分类号： A61K31/336 , A01N43/20 , A01N43/90 , A01N45/00 , C07D301/32 , C07D303/14 , C07D303/32 , C07D493/04 , A01N53/00 , C07D303/44 , C07D303/17 , A61K9/00 , A61K9/06 , A61K47/10
摘要： The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment
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公开(公告)号：US10543188B2
公开(公告)日：2020-01-28
申请号：US16149977
申请日：2018-10-02
申请人： QBIOTICS PTY LTD
IPC分类号： A61K31/336 , A01N43/20 , A01N43/90 , A01N45/00 , C07D301/32 , C07D303/14 , C07D303/32 , C07D493/04 , A01N53/00 , C07D303/44 , C07D303/17 , A61K9/00 , A61K9/06 , A61K47/10
摘要： The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment.
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公开(公告)号：US11213506B2
公开(公告)日：2022-01-04
申请号：US16496333
申请日：2018-03-23
申请人： QBIOTICS PTY LTD
发明人： Paul Warren Reddell , Jason Kingsley Cullen , Glen Mathew Boyle , Peter Gordon Parsons , Victoria Anne Gordon
IPC分类号： A61K31/336 , A61K39/395 , A61K9/00 , A61P35/00
摘要： The present invention relates to a combination therapy for tumours comprising the administration of an epoxytigliane compound and an immune checkpoint inhibitor. In particular embodiments, there is a method of treating a tumour and/or treating or preventing one or more bystander tumours with the therapy. Pharmaceutical compositions and kits containing epoxytigliane compounds and immune checkpoint inhibitors are also described.
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公开(公告)号：US20210196668A1
公开(公告)日：2021-07-01
申请号：US17204747
申请日：2021-03-17
申请人： QBIOTICS PTY LTD
IPC分类号： A61K31/336 , A01N43/20 , A01N43/90 , A01N45/00 , C07D301/32 , C07D303/14 , C07D303/32 , C07D493/04 , A01N53/00 , C07D303/44 , C07D303/17 , A61K9/00 , A61K9/06 , A61K47/10
摘要： The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment
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