公开(公告)号：US20240002368A1

公开(公告)日：2024-01-04

申请号：US18037965

申请日：2021-11-23

Applicant: QILU REGOR THERAPEUTICS INC.

Inventor： Hailong Li ,  Wenge Zhong ,  Wei Huang

IPC: C07D403/12 ,  C07D471/04 ,  C07D405/14 ,  C07D403/14 ,  C07D413/14

CPC classification number: C07D403/12 ,  C07D471/04 ,  C07D405/14 ,  C07D403/14 ,  C07D413/14

Abstract: The present disclosure provides compounds of Formula (I) a pharmaceutically acceptable salt, a stereoisomer, or a tautomer thereof, for use in, e.g. treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.