公开(公告)号：US20240294989A1

公开(公告)日：2024-09-05

申请号：US18662594

申请日：2024-05-13

Applicant: Quest Diagnostics Investments LLC

Inventor： Heather SANDERS ,  Kevin QU ,  James PRENTICE ,  Frederic WALDMAN

IPC: C12Q1/6886

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.

公开(公告)号：US20240263248A1

公开(公告)日：2024-08-08

申请号：US18635818

申请日：2024-04-15

Applicant: Quest Diagnostics Investments LLC

Inventor： Kevin QU ,  Anthony Sferruzza ,  Ke Zhang ,  Yan Liu ,  Renius Owen

IPC: C12Q1/6886

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Provided herein are methods for miRNA profiling for the diagnosis, prognosis, and management of melanoma and differentiation of melanoma from nevi.

公开(公告)号：US20210324468A1

公开(公告)日：2021-10-21

申请号：US17361809

申请日：2021-06-29

Applicant: Quest Diagnostics Investments LLC

Inventor： Shih-Min CHENG ,  Joseph J. CATANESE ,  Andrew GRUPE ,  Feras HANTASH ,  Frederic M. WALDMAN ,  Kevin QU

IPC: C12Q1/6874 ,  C12Q1/6886 ,  C12Q1/6869 ,  C12N15/10

Abstract: The present technology relates to methods for determining whether a patient having thyroid nodules with indeterminate cytology will benefit from diagnostic surgery, e.g., lobectomy. These methods are based on screening a patient's thyroid nodules and detecting alterations in target nucleic acid sequences corresponding to a specific set of thyroid cancer-related genes. Kits for use in practicing the methods are also provided.

公开(公告)号：US20190112653A1

公开(公告)日：2019-04-18

申请号：US16067189

申请日：2016-12-30

Applicant: Quest Diagnostics Investments LLC

Inventor： Shih-Min CHENG ,  Joseph J. CATANESE ,  Andrew GRUPE ,  Feras HANTASH ,  Frederic M. WALDMAN ,  Kevin QU

IPC: C12Q1/6874 ,  C12Q1/6886 ,  C12N15/10

Abstract: The present technology relates to methods for determining whether a patient having thyroid nodules with indeterminate cytology will benefit from diagnostic surgery, e.g., lobectomy. These methods are based on screening a patient's thyroid nodules and detecting alterations in target nucleic acid sequences corresponding to a specific set of thyroid cancer-related genes. Kits for use in practicing the methods are also provided.