公开(公告)号：US20230174664A1

公开(公告)日：2023-06-08

申请号：US17779720

申请日：2020-11-25

Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.

Inventor： Vered PADLER-KARAVANI ,  Ron AMON ,  Ronit ROSENFELD

IPC: C07K16/28 ,  A61K47/68 ,  A61P35/00 ,  G01N33/574

CPC classification number: C07K16/2896 ,  A61K47/6849 ,  A61P35/00 ,  G01N33/57492 ,  C07K2317/92 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/734 ,  G01N2400/02

Abstract: The present invention discloses novel monoclonal antibodies and functional fragments thereof that specifically bind to SLeA carbohydrate antigen with high specificity and selectivity. The invention further provides compositions comprising the antibodies or fragments thereof as well as uses of the antibodies, fragments and compositions.