公开(公告)号：US20160237148A1

公开(公告)日：2016-08-18

申请号：US15144574

申请日：2016-05-02

Applicant: REGENERON PHARMACEUTICALS, INC.

Inventor： Lynn MACDONALD ,  Richard TORRES ,  Marc R. MORRA ,  Joel H. MARTIN ,  Joel C. REINHARDT ,  Paul TISEO

IPC: C07K16/22 ,  A61K39/395 ,  A61K45/06 ,  A61K9/00

CPC classification number: C07K16/22 ,  A61K9/0019 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76

Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.

公开(公告)号：US20190211090A1

公开(公告)日：2019-07-11

申请号：US16282120

申请日：2019-02-21

Applicant: REGENERON PHARMACEUTICALS, INC.

Inventor： Lynn MACDONALD ,  Richard TORRES ,  Marc R. MORRA ,  Joel H. MARTIN ,  Joel C. REINHARDT ,  Paul TISEO

IPC: C07K16/22 ,  A61K45/06 ,  A61K9/00 ,  A61K39/395

Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.

公开(公告)号：US20200339672A1

公开(公告)日：2020-10-29

申请号：US16926232

申请日：2020-07-10

Applicant: REGENERON PHARMACEUTICALS, INC.

Inventor： Lynn MACDONALD ,  Richard TORRES ,  Marc R. MORRA ,  Joel H. MARTIN ,  Joel C. REINHARDT ,  Paul TISEO

IPC: C07K16/22 ,  A61K39/395 ,  A61K45/06 ,  A61K9/00

Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.