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公开(公告)号：US10172874B2
公开(公告)日：2019-01-08
申请号：US15935862
申请日：2018-03-26
发明人： Gavin Hirst , Raja Reddy , Scott Hecker , Maxim Totrov , David C. Griffith , Olga Rodny , Michael N. Dudley , Serge Boyer
IPC分类号： A61K31/69 , A61K45/06 , C07F5/02 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/4439 , A61K31/546 , A61K9/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
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公开(公告)号：US09642869B2
公开(公告)日：2017-05-09
申请号：US14146671
申请日：2014-01-02
发明人： Raja K. Reddy , Tomasz Glinka , Maxim Totrov , Scott Hecker
IPC分类号： A61K31/69 , C07F5/04 , A61K45/06 , C07F5/02 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546
CPC分类号： A61K31/69 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546 , A61K45/06 , C07F5/025 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents. Other embodiments relate to pharmaceutical compositions containing boronic acid derivatives and additional excipient such as meglumine.
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公开(公告)号：US20140194384A1
公开(公告)日：2014-07-10
申请号：US14146643
申请日：2014-01-02
发明人： Raja K. Reddy , Tomasz Glinka , Maxim Totrov , Scott Hecker
CPC分类号： A61K31/69 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546 , A61K45/06 , C07F5/025 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
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公开(公告)号：US20140194382A1
公开(公告)日：2014-07-10
申请号：US13829687
申请日：2013-03-14
发明人： Raja Reddy , Tomasz Glinka , Maxim Totrov , Scott Hecker
CPC分类号： A61K31/69 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546 , A61K45/06 , C07F5/02 , C07F5/025 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
摘要翻译： 本文公开了抗微生物化合物组合物，药物组合物，其用途和制备。 一些实施方案涉及硼酸衍生物及其作为治疗剂的用途。
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5.发明申请公开(公告)号：US20190076449A1
公开(公告)日：2019-03-14
申请号：US16188982
申请日：2018-11-13
发明人： Gavin Hirst , Raja Reddy , Scott Hecker , Maxim Totrov , David C. Griffith , Olga Rodny , Michael N. Dudley , Serge Boyer
IPC分类号： A61K31/69 , A61K9/00 , A61K31/546 , A61K31/4439 , A61K31/427 , A61K31/4196 , A61K31/407 , C07F5/02 , A61K45/06
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
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公开(公告)号：US09132140B2
公开(公告)日：2015-09-15
申请号：US14146643
申请日：2014-01-02
发明人： Raja K. Reddy , Tomasz Glinka , Maxim Totrov , Scott Hecker
IPC分类号： A61K31/69 , C07F5/04 , A61K45/06 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546 , C07F5/02
CPC分类号： A61K31/69 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546 , A61K45/06 , C07F5/025 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
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公开(公告)号：US20140194385A1
公开(公告)日：2014-07-10
申请号：US14146671
申请日：2014-01-02
发明人： Raja K. Reddy , Tomasz Glinka , Maxim Totrov , Scott Hecker
CPC分类号： A61K31/69 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/546 , A61K45/06 , C07F5/025 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents. Other embodiments relate to pharmaceutical compositions containing boronic acid derivatives and additional excipient such as meglumine.
摘要翻译： 本文公开了抗微生物化合物组合物，药物组合物，其用途和制备。 一些实施方案涉及硼酸衍生物及其作为治疗剂的用途。 其它实施方案涉及含有硼酸衍生物和附加赋形剂如葡甲胺的药物组合物。
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8.发明申请公开(公告)号：US20180214465A1
公开(公告)日：2018-08-02
申请号：US15935782
申请日：2018-03-26
发明人： Gavin Hirst , Raja Reddy , Scott Hecker , Maxim Totrov , David C. Griffith , Olga Rodny , Michael N. Dudley , Serge Boyer
IPC分类号： A61K31/69 , C07F5/02 , A61K45/06 , A61K31/546 , A61K31/4439 , A61K9/00 , A61K31/4196 , A61K31/407 , A61K31/427
CPC分类号： A61K31/69 , A61K9/0019 , A61K9/0053 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/4439 , A61K31/546 , A61K45/06 , C07F5/025 , Y02A50/401 , Y02A50/406 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
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公开(公告)号：US09963467B2
公开(公告)日：2018-05-08
申请号：US15312173
申请日：2015-05-18
发明人： Raja Reddy , Tomasz Glinka , Scott Hecker , Maxim Totrov , Olga Rodny
IPC分类号： A61K31/69 , C07F5/02 , A61K31/407 , A61K31/43 , A61K31/545 , A61K31/546 , A61K31/4196 , A61K31/427 , A61K45/06 , A61K47/26
CPC分类号： C07F5/025 , A61K31/407 , A61K31/4196 , A61K31/427 , A61K31/43 , A61K31/545 , A61K31/546 , A61K31/69 , A61K45/06 , A61K47/26 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
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公开(公告)号：US20170136047A1
公开(公告)日：2017-05-18
申请号：US15323081
申请日：2015-06-29
发明人： Raja K. Reddy , Tomasz Glinka , Maxim Totrov , Scott Hecker , Olga Rodny
IPC分类号： A61K31/69 , A61K31/407 , A61K31/427 , C07F5/02
CPC分类号： A61K31/69 , A61K31/407 , A61K31/427 , A61K45/06 , C07F5/025 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
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