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公开(公告)号：US20230339863A1
公开(公告)日：2023-10-26
申请号：US17796419
申请日：2021-01-29
Applicant: RESEARCH TRIANGLE INSTITUTE
Inventor： George AMATO , Rangan MAITRA , Scott P. RUNYON
IPC: C07D231/56
CPC classification number: C07D231/56
Abstract: The present disclosure includes peripheral partial agonists of one or more CB receptors, including modulation of CB1, both with and without CB2 selectivity. The compounds of the present disclosure may be useful in the treatment of diseases and disorders mediated by a CB-signaling pathway, including but not limited to pain, gastrointestinal disorders, metabolic disorders, and liver disorders, such as alcoholic steatohepatitis or nonalcoholic steatohepatitis (NASH).
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