公开(公告)号：US10238595B2

公开(公告)日：2019-03-26

申请号：US15807711

申请日：2017-11-09

Applicant: RHODIA OPERATIONS

Inventor： Robert Lee Reierson ,  Denis Bendejacq

IPC: A61K8/81 ,  C07F9/09 ,  A61Q11/00 ,  C07F9/572

Abstract: An oral care composition in the form of a toothpaste, tooth gel, dentifrice, tooth powder, prophy paste, mouthwash, rinse, tooth mousse, dental floss, chewing gum, soluble oral care strip or film for direct application or attachment to an oral surface, or lozenge for combating dental caries, erosion, hypersensitivity, and/or staining that includes an orally acceptable carrier and a copolymer of a first α, β-ethylenically unsaturated phosphate compound (A); and one or more α, β-ethylenically unsaturated co-monomers, at least one of which is other than an allyl-functional co-monomer, wherein (A) is an allyl phosphate compound of formula (A): [CH2═CH—CH2—O(R1O)a(R2O)b]xP(O)(OM)3-x  (A) wherein, R1 is a substituted or unsubstituted (C2-C4) alkylene moiety; R2 is a substituted or unsubstituted (C2-C4) alkylene moiety; M is identical or different, hydrogen, alkali metal, ammonium, protonated alkyl amine, protonated alkanolamine, or protonated basic amino acid; X is 1 or 2, a is from 1 to 20; and b is from 0 to 20. Methods for combating dental caries, erosion, hypersensitivity, and/or staining are also provided.

公开(公告)号：US09839599B2

公开(公告)日：2017-12-12

申请号：US14940804

申请日：2015-11-13

Applicant: RHODIA OPERATIONS

Inventor： Robert Lee Reierson ,  Denis Bendejacq

IPC: A61K8/81 ,  A61Q11/00 ,  C07F9/572 ,  C07F9/09

CPC classification number: A61K8/817 ,  A61K8/8164 ,  A61K2800/28 ,  A61Q11/00 ,  C07F9/091 ,  C07F9/572

Abstract: An oral care composition in the form of a toothpaste, tooth gel, dentifrice, tooth powder, prophy paste, mouthwash, rinse, tooth mousse, dental floss, chewing gum, soluble oral care strip or film for direct application or attachment to an oral surface, or lozenge for combating dental caries, erosion, hypersensitivity, and/or staining that includes an orally acceptable carrier and a copolymer of a first α,β-ethylenically unsaturated phosphate compound (A); and one or more α,β-ethylenically unsaturated co-monomers, at least one of which is other than an allyl-functional co-monomer, wherein (A) is an allyl phosphate compound of formula (A): [CH2═CH—CH2—O(R1O)a(R2O)b]xP(O)(OM)3-x   (A) wherein, R1 is a substituted or unsubstituted (C2-C4) alkylene moiety; R2 is a substituted or unsubstituted (C2-C4) alkylene moiety; M is identical or different, hydrogen, alkali metal, ammonium, protonated alkyl amine, protonated alkanolamine, or protonated basic amino acid; X is 1 or 2, a is from 1 to 20; and b is from 0 to 20. Methods for combating dental caries, erosion, hypersensitivity, and/or staining are also provided.