公开(公告)号：US20130203628A1

公开(公告)日：2013-08-08

申请号：US13862530

申请日：2013-04-15

Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.

Inventor： Frank Bergmann ,  Walter Eberle ,  Thomas Fischer ,  Herbert von der Eltz

IPC: C12Q1/68

CPC classification number: C12Q1/6841 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2565/1025 ,  C12Q2563/107

Abstract: The present disclosure relates to a set of at least 100 single-stranded oligonucleotide probes directed against (or complementary to) portions of a genomic target sequence of interest. The present disclosure also relates to a method of detecting a genomic target sequence of interest using the set of oligonucleotide probes and a method of generating the set of oligonucleotide probes. Further, the present disclosure relates to a kit comprising the set of oligonucleotide probes and at least one further component.

Abstract translation: 本公开内容涉及针对感兴趣的基因组靶序列的（或互补）部分的一组至少100个单链寡核苷酸探针。 本公开还涉及使用该组寡核苷酸探针检测感兴趣的基因组靶序列的方法和产生寡核苷酸探针组的方法。 此外，本公开涉及包含该组寡核苷酸探针和至少一种另外的组分的试剂盒。