公开(公告)号：US20170073775A1

公开(公告)日：2017-03-16

申请号：US15363822

申请日：2016-11-29

Applicant: ROSETTA GENOMICS LTD. ,  MOR RESEARCH APPLICATIONS

Inventor： Moshe Hosen ,  Gila Lithwick Yanai ,  Ram Eitan

IPC: C12Q1/68 ,  A61K45/00 ,  A61K31/713

CPC classification number: C12Q1/6886 ,  A61K31/713 ,  A61K45/00 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/16 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention farther provides methods for distinguishing between histological subtypes of ovarian cancer tumors, and also methods and compositions liar the treatment or prevention of ovarian cancer. Specifically the invention relates to microRNA molecules associated with said methods and compositions, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了用于预测卵巢癌患者预后的组合物和方法。 本发明还提供了区分卵巢癌肿瘤的组织学亚型的方法，还涉及治疗或预防卵巢癌的方法和组合物。 具体地说，本发明涉及与所述方法和组合物相关的微小RNA分子，以及与之有关的或从其衍生的各种核酸分子。

公开(公告)号：US09988690B2

公开(公告)日：2018-06-05

申请号：US15363822

申请日：2016-11-29

Applicant: ROSETTA GENOMICS LTD. ,  MOR RESEARCH APPLICATIONS

Inventor： Moshe Hoshen ,  Gila Lithwick Yanai ,  Ram Eitan

IPC: C12Q1/68 ,  A61K31/713 ,  A61K45/00

CPC classification number: C12Q1/6886 ,  A61K31/713 ,  A61K45/00 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/16 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention further provides methods for distinguishing between histological subtypes of ovarian cancer tumors, and also methods and compositions for the treatment or prevention of ovarian cancer. Specifically the invention relates to microRNA molecules associated with said methods and compositions, as well as various nucleic acid molecules relating thereto or derived therefrom.

公开(公告)号：US20190112665A1

公开(公告)日：2019-04-18

申请号：US15975533

申请日：2018-05-09

Applicant: ROSETTA GENOMICS LTD. ,  MOR RESEARCH APPLICATIONS

Inventor： Moshe Hoshen ,  Gila Lithwick Yanai ,  Ram Eitan

IPC: C12Q1/6886 ,  A61K31/713 ,  A61K45/00

Abstract: Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention further provides methods for distinguishing between histological subtypes of ovarian cancer tumors, and also methods and compositions for the treatment or prevention of ovarian cancer. Specifically the invention relates to microRNA molecules associated with said methods and compositions, as well as various nucleic acid molecules relating thereto or derived therefrom.