公开(公告)号：US10350179B2

公开(公告)日：2019-07-16

申请号：US15577439

申请日：2016-05-31

申请人： Raffaele MIGLIACCIO

发明人： Raffaele Migliaccio ,  Antonella Sardei ,  Carmela Migliaccio

IPC分类号： A61K31/164 ,  A61K31/01 ,  A61P29/00

摘要： The object of the present invention is the combination of palmitoylethanolamide (PEA) and lycopene, and/or pharmaceutically acceptable salts and/or derivatives thereof, the pharmaceutical formulations comprising the combination of PEA and lycopene, and/or pharmaceutically acceptable salts or derivatives thereof, optionally together with at least one pharmacologically acceptable excipient, and the use of the combination of PEA and lycopene, and/or pharmaceutically acceptable salts or derivatives thereof, and of the formulations comprising such a combination, in the treatment of inflammatory diseases.

公开(公告)号：US10149827B2

公开(公告)日：2018-12-11

申请号：US15946950

申请日：2018-04-06

申请人： Raffaele Migliaccio

发明人： Raffaele Migliaccio ,  Antonella Sardei ,  Carmela Miglicaccio

IPC分类号： A61K31/202 ,  A61K9/06 ,  A61K9/00 ,  A61K31/164 ,  A61K31/20 ,  A61K31/201

摘要： The present invention relates to a mixture containing up to two fatty acids selected from palmitic acid, oleic acid, stearic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, azelaic acid and myristic acid and palmitoylethanolamide. In one embodiment of the present invention said mixture is characterized in that at least one of said up to two fatty acids is saturated. The present invention also relates to the use of the aforesaid mixture in the treatment of inflammatory and allergic pathologies.

公开(公告)号：US09962355B2

公开(公告)日：2018-05-08

申请号：US15502316

申请日：2015-08-03

申请人： Raffaele Migliaccio

发明人： Raffaele Migliaccio ,  Antonella Sardei ,  Carmela Migliaccio

IPC分类号： A61K31/202 ,  A61K9/00 ,  A61K31/164 ,  A61K31/20 ,  A61K9/06

CPC分类号： A61K31/202 ,  A61K9/0014 ,  A61K9/0034 ,  A61K9/0036 ,  A61K9/0046 ,  A61K9/0048 ,  A61K9/06 ,  A61K31/164 ,  A61K31/20 ,  A61K31/201 ,  A61K2300/00

摘要： The present invention relates to a mixture containing up to two fatty acids selected from palmitic acid, oleic acid, stearic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, azelaic acid and myristic acid and palmitoylethanolamide. In one embodiment of the present invention said mixture is characterized in that at least one of said up to two fatty acids is saturated. The present invention also relates to the use of the aforesaid mixture in the treatment of inflammatory and allergic pathologies.