公开(公告)号：US20240342181A1

公开(公告)日：2024-10-17

申请号：US18299416

申请日：2023-04-12

申请人： Xygenyx Inc.

发明人： Alexy Goldstein

IPC分类号： A61K31/52 ,  A61K9/00 ,  A61K31/20 ,  A61K31/201 ,  A61K31/205

CPC分类号： A61K31/52 ,  A61K9/0053 ,  A61K31/20 ,  A61K31/201 ,  A61K31/205

摘要： A method and compositions of treatment for improving metabolic performance using supplementation, comprising the step of applying a supplement formulation to a human subject via a selected administration route, the supplement formulation comprising therapeutically effective amounts of a plurality of medium-chain triglycerides, a plurality of amino acids, and zeatin. The plurality of medium-chain triglycerides may comprise caprylic acid, and the plurality of amino acids may comprise carnitine which may be provided in the form of L-carnitine fumarate.

公开(公告)号：US20240238237A1

公开(公告)日：2024-07-18

申请号：US18289409

申请日：2022-05-04

申请人： VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.

发明人： Deborah J. Good

IPC分类号： A61K31/201 ,  A61P1/14 ,  A61P3/04 ,  A61P5/24

CPC分类号： A61K31/201 ,  A61P1/14 ,  A61P3/04 ,  A61P5/24

摘要： Described in certain example embodiments herein are methods of and compositions for treating a Snordl l6 deficiency disease or symptom thereof with conjugated linoleic acid (CLA) or a formulation thereof. In some embodiments, the Snordl l6 deficiency disease is Prader-Willi Syndrome. Described in certain example embodiments herein are methods of and compositions for treating Nhlh2 associated hypogonadism with CLA or a formulation thereof.

公开(公告)号：US20240216456A1

公开(公告)日：2024-07-04

申请号：US18599039

申请日：2024-03-07

申请人： Nodari RIZUN

发明人： Nodari RIZUN

IPC分类号： A61K36/47 ,  A61K31/047 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/352 ,  A61K36/185 ,  A61K36/48 ,  A61K36/61 ,  A61K36/752 ,  A61K36/76 ,  A61K36/835

CPC分类号： A61K36/47 ,  A61K31/047 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/352 ,  A61K36/185 ,  A61K36/48 ,  A61K36/61 ,  A61K36/752 ,  A61K36/76 ,  A61K36/835

摘要： Compositions and methods of manufacturing mineral pitch resin compositions comprising at least one of a cannabinoid, a terpene, a terpenoid, an essential oil and a fatty acid are provided. Such mineral pitch resin compositions may be safely consumed orally, topically or otherwise, and have numerous health benefits.

公开(公告)号：US11992555B2

公开(公告)日：2024-05-28

申请号：US17448263

申请日：2021-09-21

申请人： Infirst Healthcare Limited

发明人： Robin M. Bannister ,  John Brew ,  Richard R. Reiley, III ,  Wilson Caparros Wanderley

IPC分类号： A61K9/08 ,  A61K9/14 ,  A61K31/12 ,  A61K31/137 ,  A61K31/167 ,  A61K31/192 ,  A61K31/196 ,  A61K31/216 ,  A61K31/25 ,  A61K31/337 ,  A61K31/357 ,  A61K31/366 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/522 ,  A61K31/60 ,  A61K31/616 ,  A61K31/704 ,  A61K47/10 ,  A61K47/14 ,  A61K31/19 ,  A61K31/201

CPC分类号： A61K9/08 ,  A61K9/148 ,  A61K31/12 ,  A61K31/137 ,  A61K31/167 ,  A61K31/192 ,  A61K31/196 ,  A61K31/216 ,  A61K31/357 ,  A61K31/366 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/522 ,  A61K31/60 ,  A61K31/616 ,  A61K47/10 ,  A61K47/14 ,  A61K31/19 ,  A61K31/201 ,  A61K31/25 ,  A61K31/337 ,  A61K31/704

摘要： The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.

公开(公告)号：US20240130994A1

公开(公告)日：2024-04-25

申请号：US18176094

申请日：2023-02-28

申请人： i2O Therapeutics, Inc.

发明人： Tyler Brown ,  Kelly IBSEN

IPC分类号： A61K31/205 ,  A61K31/185 ,  A61K31/191 ,  A61K31/192 ,  A61K31/194 ,  A61K31/195 ,  A61K31/198 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/222 ,  A61K31/352 ,  A61K31/375 ,  A61K31/385 ,  A61K31/4015 ,  A61K31/575 ,  A61K33/42 ,  A61K38/17 ,  A61P3/10

CPC分类号： A61K31/205 ,  A61K31/185 ,  A61K31/191 ,  A61K31/192 ,  A61K31/194 ,  A61K31/195 ,  A61K31/198 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/222 ,  A61K31/352 ,  A61K31/375 ,  A61K31/385 ,  A61K31/4015 ,  A61K31/575 ,  A61K33/42 ,  A61K38/1796 ,  A61P3/10

摘要： Disclosed herein are ionic liquids and deep eutectic liquids for the treatment of diabetes and related diseases including obesity and metabolic disorders.

公开(公告)号：US20240115535A1

公开(公告)日：2024-04-11

申请号：US18275972

申请日：2022-02-07

申请人： Peter MILNER ,  Mikhail Sergeevich SHCHEPINOV ,  Retrotope, Inc.

发明人： Peter Milner ,  Mikhail Sergeevich Shchepinov

IPC分类号： A61K31/201 ,  A61P25/28 ,  G01N33/50 ,  G01N33/555

CPC分类号： A61K31/201 ,  A61P25/28 ,  G01N33/5044 ,  G01N33/555

摘要： Disclosed are methods for inhibiting the progression of neurodegenerative disease. The methods include administering to a patient suffering from such a disease a composition comprising deuterated arachidonic acid or an ester thereof.

公开(公告)号：US11918617B2

公开(公告)日：2024-03-05

申请号：US16753512

申请日：2018-10-03

申请人： NEILOS S.R.L.

发明人： Umberto Di Maio

IPC分类号： A61K36/537 ,  A61K9/00 ,  A61K31/12 ,  A61K31/201 ,  A61K31/385 ,  A61K36/30 ,  A61P25/02

CPC分类号： A61K36/537 ,  A61K9/0053 ,  A61K9/0056 ,  A61K31/12 ,  A61K31/201 ,  A61K31/385 ,  A61K36/30 ,  A61P25/02

摘要： The present invention relates to a composition comprising α-lipoic acid, Salvia miltiorrhiza extract and Curcumin, optionally further comprising γ-linolenic acid or borage oil. Furthermore, the present invention relates to the use of such composition for treating neuropathies.

公开(公告)号：US11911425B2

公开(公告)日：2024-02-27

申请号：US17535804

申请日：2021-11-26

申请人： IDUNN TECHNOLOGIES

发明人： Eric Simard ,  Vladimir Titorenko

IPC分类号： A61K36/00 ,  A61K36/16 ,  A61K36/84 ,  A61Q19/08 ,  A61K31/05 ,  A61K31/132 ,  A61K31/155 ,  A61K31/201 ,  A61K36/185 ,  A61K36/23 ,  A61K36/71 ,  A61K36/76 ,  A61K8/44 ,  A61K8/9771 ,  A61K8/9789 ,  A61P43/00 ,  A61K8/34 ,  A61K8/365 ,  A61K8/41 ,  A61K8/43

CPC分类号： A61K36/16 ,  A61K8/347 ,  A61K8/365 ,  A61K8/41 ,  A61K8/43 ,  A61K8/44 ,  A61K8/9771 ,  A61K8/9789 ,  A61K31/05 ,  A61K31/132 ,  A61K31/155 ,  A61K31/201 ,  A61K36/185 ,  A61K36/23 ,  A61K36/71 ,  A61K36/76 ,  A61K36/84 ,  A61P43/00 ,  A61Q19/08 ,  A61K2800/5922 ,  A61K2800/78 ,  A61K36/16 ,  A61K2300/00 ,  A61K36/23 ,  A61K2300/00 ,  A61K36/76 ,  A61K2300/00 ,  A61K36/185 ,  A61K2300/00 ,  A61K36/71 ,  A61K2300/00 ,  A61K36/84 ,  A61K2300/00 ,  A61K31/05 ,  A61K2300/00 ,  A61K31/155 ,  A61K2300/00 ,  A61K31/201 ,  A61K2300/00 ,  A61K31/132 ,  A61K2300/00

摘要： The present description relates to an anti-aging composition comprising at least one plant extract. The composition can comprise at least two different anti-aging agents, wherein one the anti-aging agent is a plant extract. The combination of two anti-aging agents has a superior effect on regulating longevity compared to the use of one anti-aging agent. The plant extract is preferably selected from the group consisting of a Black cohosh extract, a Valerian extract, a Ginkgo biloba extract, a Celery seed extract, a White willow extract and a Passion flower extract.

公开(公告)号：US11890294B2

公开(公告)日：2024-02-06

申请号：US17500604

申请日：2021-10-13

申请人： HYPHENS PHARMA PTE. LTD.

发明人： Kevin Hammond ,  Adrian Davis

IPC分类号： A61K31/7032 ,  A61K9/00 ,  A61K31/164 ,  A61K31/191 ,  A61K31/201 ,  A61K31/365 ,  A61K31/575 ,  A61K33/30 ,  A61K47/10 ,  A61K47/14 ,  A61K9/06

CPC分类号： A61K31/7032 ,  A61K9/0014 ,  A61K31/164 ,  A61K31/191 ,  A61K31/201 ,  A61K31/365 ,  A61K31/575 ,  A61K33/30 ,  A61K47/10 ,  A61K47/14 ,  A61K9/06

摘要： The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin.

公开(公告)号：US20240025870A1

公开(公告)日：2024-01-25

申请号：US18375745

申请日：2023-10-02

申请人： Synaptogenix, Inc.

发明人： Thomas J. NELSON ,  Daniel L. ALKON

IPC分类号： C07D303/42 ,  A61K31/045 ,  A61K31/23 ,  A61K31/231 ,  A61K31/335 ,  A61P25/00 ,  A61P25/28 ,  A61K31/201 ,  C07C31/13 ,  C07C31/133 ,  C07C53/134 ,  C07C69/608 ,  C07D303/40 ,  C12N9/12

CPC分类号： C07D303/42 ,  A61K31/045 ,  A61K31/23 ,  A61K31/231 ,  A61K31/335 ,  A61P25/00 ,  A61P25/28 ,  A61K31/201 ,  C07C31/13 ,  C07C31/1333 ,  C07C53/134 ,  C07C69/608 ,  C07D303/40 ,  C12N9/12 ,  C12Y207/11013

摘要： The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimers disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.