公开(公告)号：US20090053306A1

公开(公告)日：2009-02-26

申请号：US11992806

申请日：2006-09-28

申请人： Rajesh K. Agarwal ,  Rampurna Prasad Gullapalli ,  Michael Martin ,  Michael Morgan ,  Dennis Chapman ,  Joseph Belier Speer ,  Yun Shan

发明人： Rajesh K. Agarwal ,  Rampurna Prasad Gullapalli ,  Michael Martin ,  Michael Morgan ,  Dennis Chapman ,  Joseph Belier Speer ,  Yun Shan

IPC分类号： A61K31/415 ,  A61K9/48

CPC分类号： A61K9/4858 ,  A61K9/4866 ,  A61K31/415 ,  Y02A50/467

摘要： The present invention relates to certain pharmaceutical compositions of a 5-HT2A serotonin receptor modulator and methods for preparing pharmaceutical composition related thereto. The pharmaceutical compositions are useful in the treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

摘要翻译： 本发明涉及5-HT2A 5-羟色胺受体调节剂的某些药物组合物及其制备药物组合物的方法。 药物组合物可用于治疗血小板聚集，冠状动脉疾病，心肌梗塞，短暂性脑缺血发作，心绞痛，中风，心房颤动，降低血块形成风险，哮喘或其症状，躁动或症状，行为障碍 ，药物诱发的精神病，精神病，精神病，吉非替尼杜勒特综合征，躁狂症，有机或NOS精神病，精神病，精神病，急性精神分裂症，慢性精神分裂症，精神分裂症，精神分裂症和相关疾病，睡眠障碍，糖尿病相关疾病，进行性多灶性白质脑病 等等。