公开(公告)号：US20090053306A1

公开(公告)日：2009-02-26

申请号：US11992806

申请日：2006-09-28

申请人： Rajesh K. Agarwal ,  Rampurna Prasad Gullapalli ,  Michael Martin ,  Michael Morgan ,  Dennis Chapman ,  Joseph Belier Speer ,  Yun Shan

发明人： Rajesh K. Agarwal ,  Rampurna Prasad Gullapalli ,  Michael Martin ,  Michael Morgan ,  Dennis Chapman ,  Joseph Belier Speer ,  Yun Shan

IPC分类号： A61K31/415 ,  A61K9/48

CPC分类号： A61K9/4858 ,  A61K9/4866 ,  A61K31/415 ,  Y02A50/467

摘要： The present invention relates to certain pharmaceutical compositions of a 5-HT2A serotonin receptor modulator and methods for preparing pharmaceutical composition related thereto. The pharmaceutical compositions are useful in the treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

摘要翻译： 本发明涉及5-HT2A 5-羟色胺受体调节剂的某些药物组合物及其制备药物组合物的方法。 药物组合物可用于治疗血小板聚集，冠状动脉疾病，心肌梗塞，短暂性脑缺血发作，心绞痛，中风，心房颤动，降低血块形成风险，哮喘或其症状，躁动或症状，行为障碍 ，药物诱发的精神病，精神病，精神病，吉非替尼杜勒特综合征，躁狂症，有机或NOS精神病，精神病，精神病，急性精神分裂症，慢性精神分裂症，精神分裂症，精神分裂症和相关疾病，睡眠障碍，糖尿病相关疾病，进行性多灶性白质脑病 等等。

公开(公告)号：US08048454B2

公开(公告)日：2011-11-01

申请号：US10598671

申请日：2005-03-09

申请人： Michael Martin

发明人： Michael Martin

IPC分类号： A61K33/14 ,  A61K33/00 ,  A61P43/00 ,  A61P31/04

CPC分类号： A61K33/14 ,  Y02A50/402 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/414 ,  Y02A50/423 ,  Y02A50/469 ,  Y02A50/471 ,  Y02A50/473 ,  Y02A50/475 ,  Y02A50/478 ,  Y02A50/479 ,  Y02A50/481 ,  Y02A50/483 ,  Y10S514/921

摘要： This invention relates generally to a method of treating inflammation and associated diseases and disorders by administering an agent that inhibits glycogen synthase kinase 3 activity.

摘要翻译： 本发明一般涉及通过施用抑制糖原合酶激酶3活性的药物来治疗炎症和相关疾病和病症的方法。

公开(公告)号：US20100322698A1

公开(公告)日：2010-12-23

申请号：US12486562

申请日：2009-06-17

申请人： Michael Martin

发明人： Michael Martin

IPC分类号： B43K23/02

CPC分类号： B43K23/02 ,  B43K7/005 ,  B43K7/02 ,  B43K23/04 ,  B43K29/00

摘要： The writing instrument mountable to a ferrous surface includes an ink barrel of a non-ferrous material and first and second ends, an interior ink receiving space defined by an interior surface thereof, and a longitudinally extending axis. An agitator is positioned within the interior ink receiving space and is freely slidable therein for reciprocation along the longitudinally extending axis. The agitator includes a continuously open passage extending therethrough and generally in a direction from the first end towards the second end of the ink barrel. The agitator is a permanent magnet, whereby the writing instrument is detachably mountable to a surface of a ferrous material by a magnetic attraction between the surface of a ferrous material and the agitator when the ink barrel is positioned against the surface of a ferrous material.

摘要翻译： 可安装到黑色金属表面的书写工具包括有色金属材料的墨桶和第一和第二端，由其内表面限定的内部墨水容纳空间和纵向延伸的轴线。 搅拌器定位在内部油墨接收空间内并且可自由地在其中滑动以沿着纵向延伸的轴线往复运动。 搅拌器包括一个连续打开的通道，其通过其延伸，并且大致在从墨桶的第一端到第二端的方向上。 搅拌器是永久磁铁，借此当墨水筒靠着铁质材料的表面定位时，书写工具可以通过铁质材料表面和搅拌器之间的磁吸引力而可拆卸地安装到铁质材料的表面上。

公开(公告)号：US20100236341A1

公开(公告)日：2010-09-23

申请号：US12406756

申请日：2009-03-18

申请人： Michael Martin ,  Kevin Walsh ,  Julia Aebersold ,  R. Andrew McGill ,  Stanley V. Stepnowski

发明人： Michael Martin ,  Kevin Walsh ,  Julia Aebersold ,  R. Andrew McGill ,  Stanley V. Stepnowski

IPC分类号： G01N1/40 ,  G01N1/02

CPC分类号： G01N1/405 ,  G01N2001/022

摘要： An analyte collection system device includes an active area that includes a plurality of perforations extending therethrough. The plurality of perforations are arranged to permit passage of an analyte fluid flow through the microscale plate. A heating element is provided for heating the active area, and a thermal distribution layer is disposed over at least a portion of the active area. For cooling the active area at or below an ambient temperature, an active cooler is provided.

摘要翻译： 分析物收集系统装置包括有效区域，其包括穿过其中延伸的多个穿孔。 多个穿孔布置成允许分析物流体流通过微尺度板。 提供加热元件以加热有源区域，并且热分布层设置在有源区域的至少一部分上。 为了在环境温度或低于环境温度下冷却有源区域，提供有源冷却器。

公开(公告)号：US20090249958A1

公开(公告)日：2009-10-08

申请号：US12337449

申请日：2008-12-17

申请人： Scott Cambron ,  Thomas Roussel ,  Robert Keynton ,  Michael Martin ,  Kevin Walsh ,  Doug Jackson ,  John Naber

发明人： Scott Cambron ,  Thomas Roussel ,  Robert Keynton ,  Michael Martin ,  Kevin Walsh ,  Doug Jackson ,  John Naber

IPC分类号： B01D50/00

CPC分类号： G01N1/405 ,  G01N30/08 ,  G01N35/1095

摘要： An interchangeable preconcentrator assembly comprises an outer housing and an inner housing defining a chamber. A biased urging member is held at least partially within the outer housing and slidably biased toward a surface of the inner housing. When the biased urging member is at least partially retracted, a space is defined between the urging member and the surface of the inner housing for accommodating at least one preconcentrator chip. A continuous fluid flow path is defined through the outer housing and through the space. The interchangeable preconcentrator assembly may further comprise at least one modular preconcentrator carriage.

摘要翻译： 可互换的预浓缩器组件包括外壳体和限定腔室的内壳体。 偏压推动构件至少部分地保持在外壳体内并且可滑动地偏压到内壳体的表面。 当偏压推动构件至少部分地缩回时，在推动构件和内壳体的表面之间限定一个空间，用于容纳至少一个预浓缩器芯片。 连续的流体流动路径通过外部壳体并通过该空间来限定。 可互换的预浓缩器组件还可以包括至少一个模块化预浓缩器托架。

公开(公告)号：US20070169342A1

公开(公告)日：2007-07-26

申请号：US11690595

申请日：2007-03-23

申请人： Noah Lassar ,  Mohammad Akhavain ,  Michael Martin

发明人： Noah Lassar ,  Mohammad Akhavain ,  Michael Martin

IPC分类号： H05K3/00

CPC分类号： H05K1/111 ,  H01L2924/00013 ,  H05K1/0306 ,  H05K2201/09418 ,  H05K2201/09427 ,  H05K2201/09709 ,  H05K2201/10674 ,  Y02P70/611 ,  Y10T29/49147 ,  Y10T29/49149 ,  Y10T29/49165 ,  H01L2224/29099

摘要： In an implementation of connection pad layouts, a connection assembly includes a substrate assembly and connection pads disposed thereon. The connection pads form a configuration such that each connection pad is configured to align with a different terminal of an interconnect that is warped or otherwise has a non-linear alignment of terminals.

摘要翻译： 在连接焊盘布局的实现中，连接组件包括衬底组件和设置在其上的连接焊盘。 连接焊盘形成这样的配置，使得每个连接焊盘被配置成与被弯曲的互连的不同端子对齐或者具有端子的非线性对准。

公开(公告)号：US20070120938A1

公开(公告)日：2007-05-31

申请号：US11289888

申请日：2005-11-30

申请人： Anne Fitzpatrick ,  Michael Martin ,  James Stevens ,  Rosario Bracco ,  Carlos Alva ,  John Durbin

发明人： Anne Fitzpatrick ,  Michael Martin ,  James Stevens ,  Rosario Bracco ,  Carlos Alva ,  John Durbin

IPC分类号： G03G15/01

CPC分类号： G03G15/0163 ,  G03G2215/0119 ,  G03G2215/0158

摘要： Reflex writing is a group of algorithms developed to maintain color registration in xerographic systems using multiple imagers. Unlike conventional imaging, in which the individual color separations are imaged based on events in a time domain, in a reflex write implementation sequential color separations are written based on events in the spatial domain. Once the initial color separation is written, the distance that color separation travels is tracked until the color separation is under the next imaging station, where the next color separation is written properly registered with respect to the existing color separation. The imaging system includes a raster output scanner imager for the black station and a light emitting diode bar for the color station. For each black scanline written the distance the belt travels is tracked by counting machine clocks, which are based on photoreceptor module drive roll encoder pulses and related to the belt travel, and when the black latent image scanline has traveled the known distance between the two imagers, the light emitting diode scanline is written registered with respect to the raster output scanner scanline.

摘要翻译： 反射写作是开发的一组算法，用于在使用多个成像器的静电复印系统中维护颜色注册。 与基于时域中的事件对单独分色进行成像的常规成像不同，在反射写入实现中，基于空间域中的事件来编写顺序分色。 一旦写入了初始分色，跟踪颜色分离行进的距离直到颜色分离在下一个成像站之下，其中相对于现有颜色分离正确地登记下一个分色。 成像系统包括用于黑色电台的光栅输出扫描仪成像器和用于彩色电台的发光二极管条。 对于写入的每个黑色扫描线，通过计算基于感光体模块驱动辊编码器脉冲并与带行进相关的机器时钟来跟踪皮带行进的距离，并且当黑色潜像扫描线已经行进了两个成像器之间的已知距离 相对于光栅输出扫描仪扫描线，写入发光二极管扫描线。

公开(公告)号：US20070120665A1

公开(公告)日：2007-05-31

申请号：US11287817

申请日：2005-11-28

申请人： Michael Martin ,  Roger Hawkins

发明人： Michael Martin ,  Roger Hawkins

IPC分类号： G08B13/08 ,  G08B21/00

CPC分类号： B60P3/226 ,  B60P3/227 ,  H01H13/183 ,  H01H15/102

摘要： A sensor assembly, system and method for using a sensor assembly is disclosed making use of a sealed switch and an actuator that converts linear motion in a plane to linear motion in a perpendicular plane. The motion of the actuator in the perpendicular plane actuates the switch which signals that hatch is in an open position.

摘要翻译： 公开了一种用于使用传感器组件的传感器组件，系统和方法，其使用密封开关和将平面中的线性运动转换成垂直平面中的线性运动的致动器。 致动器在垂直平面上的运动致动开关，该开关指示舱口处于打开位置。

公开(公告)号：US20070111971A1

公开(公告)日：2007-05-17

申请号：US10575038

申请日：2004-10-04

申请人： John Eaddy ,  Dennis Heyer ,  Amarjit Randhawa ,  Vicente Sanano ,  John Ray ,  Subba Katamreddy ,  Michael Martin ,  Michael McClure

发明人： John Eaddy ,  Dennis Heyer ,  Amarjit Randhawa ,  Vicente Sanano ,  John Ray ,  Subba Katamreddy ,  Michael Martin ,  Michael McClure

IPC分类号： A61K31/66

CPC分类号： C07C69/017 ,  C07C59/52 ,  C07C69/63 ,  C07C69/708 ,  C07C69/732 ,  C07C69/75 ,  C07C69/78 ,  C07C69/96 ,  C07C229/10 ,  C07D261/18 ,  C07D295/15 ,  C07D307/24 ,  C07D333/40 ,  C07F9/12

摘要： Compounds of formula (I): with a variety of therapeutic uses, more particularly novel prodrugs that are particularly useful for delivering a parent compound for selective estrogen receptor modulation.

摘要翻译： 式（I）化合物：具有各种治疗用途，更特别新颖的前药，其特别可用于递送用于选择性雌激素受体调节的母体化合物。

公开(公告)号：US20070110465A1

公开(公告)日：2007-05-17

申请号：US11274523

申请日：2005-11-15

申请人： Paul Bonino ,  Ralph Shoemaker ,  Michael Martin

发明人： Paul Bonino ,  Ralph Shoemaker ,  Michael Martin

IPC分类号： G03G15/00 ,  G03G15/01

CPC分类号： G03G15/5041 ,  G03G2215/00042 ,  G03G2215/0161 ,  G03G2215/017

摘要： A xerographic system (8) includes a moving photoreceptor (10) and multiple toner development systems (12, 14) arranged to selectively dispose regions of toner on the moving photoreceptor. A toner density sensor (40) is arranged to measure toner density on the moving photoreceptor over a sensor area (A). A toner coverage monitor (64) operatively connected with the toner density sensor (40) monitors toner coverage based on measurements by the toner density sensor of toner coverage calibration regions disposed on the moving photoreceptor by the multiple toner development systems. A spatial registration monitor (66) also operatively connected with the toner density sensor (40) monitors spatial registration of the multiple toner development systems based on measurements by the toner density sensor of spatial registration calibration regions disposed on the moving photoreceptor by the multiple toner development systems.

摘要翻译： 静电复印系统（8）包括移动感光体（10）和多个调色剂显影系统（12,14），其布置成选择性地将调色剂区域配置在移动感光体上。 调色剂浓度传感器（40）布置成测量传感器区域（A）上的运动感光体上的调色剂密度。 与调色剂浓度传感器（40）可操作地连接的调色剂覆盖监视器（64）基于由多个调色剂显影系统设置在移动感光体上的调色剂覆盖校准区域的调色剂浓度传感器的测量来监测调色剂覆盖。 还可操作地与调色剂浓度传感器（40）连接的空间配准监视器（66）基于通过多个调色剂显影设置在移动感光体上的空间配准校准区域的调色剂浓度传感器的测量来监测多个调色剂显影系统的空间配准 系统。