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1.发明申请ENZYMATIC AMMONOLYSIS PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR DPP IV INHIBITORS 有权用于制备DPP IV抑制剂的中间体的酶促溶解方法公开(公告)号：US20070207527A1
公开(公告)日：2007-09-06
申请号：US11736786
申请日：2007-04-18
申请人： Ramesh Patel , Ronald Hanson , Iqbal Gill , David Brzozowski , Paul Skonezny , Michael Politino , Jason Chen , Francisco Moris-Varas , Brenda White
发明人： Ramesh Patel , Ronald Hanson , Iqbal Gill , David Brzozowski , Paul Skonezny , Michael Politino , Jason Chen , Francisco Moris-Varas , Brenda White
IPC分类号： C12P13/24
CPC分类号： C07D207/22 , C07D209/52 , C07K5/06078 , C12P13/04 , C12P17/10 , C12P17/12
摘要： An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to catalyze the ammonolysis process.
摘要翻译： 提供酶促氨解方法用于制备用于制备二肽基肽酶IV抑制剂的中间体，其中使用南极假丝酵母脂肪酶-B来催化氨解过程。
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2.发明申请Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors 有权用于制备DPP IV抑制剂中间体的酶促氨解过程公开(公告)号：US20050256019A1
公开(公告)日：2005-11-17
申请号：US11119552
申请日：2005-05-02
申请人： Ramesh Patel , Ronald Hanson , Iqbal Gill , David Brzozowski , Paul Skonezny , Michael Politino , Jason Chen , Francisco Moris-Varas , Brenda White
发明人： Ramesh Patel , Ronald Hanson , Iqbal Gill , David Brzozowski , Paul Skonezny , Michael Politino , Jason Chen , Francisco Moris-Varas , Brenda White
IPC分类号： C07D207/22 , C07D209/52 , C07K5/065 , C11D3/00 , C12P17/10
CPC分类号： C07D207/22 , C07D209/52 , C07K5/06078 , C12P13/04 , C12P17/10 , C12P17/12
摘要： An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to catalyze the ammonolysis process.
摘要翻译： 提供酶促氨解方法用于制备用于制备二肽基肽酶IV抑制剂的中间体，其中使用南极假丝酵母脂肪酶-B来催化氨解过程。
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