公开(公告)号：US06869404B2

公开(公告)日：2005-03-22

申请号：US10376063

申请日：2003-02-26

申请人： Randal C. Schulhauser ,  Gary Stefanov ,  Jon S. Tracy ,  Eric M. Rieder ,  Mark Son ,  Brian B. Lee ,  Nicole M. Haupt

发明人： Randal C. Schulhauser ,  Gary Stefanov ,  Jon S. Tracy ,  Eric M. Rieder ,  Mark Son ,  Brian B. Lee ,  Nicole M. Haupt

IPC分类号： A61B5/00 ,  A61B5/0215 ,  A61B5/0432 ,  A61B5/0456 ,  A61B7/00 ,  A61B5/02

CPC分类号： A61B5/0006 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/04325 ,  A61B5/0456 ,  A61B5/7232 ,  A61B7/003

摘要： A minimally invasive, implantable heart sound and ECG monitor and associated method for deriving blood pressure from heart sound data. The device is equipped with an acoustical sensor for detecting first and second heart sounds which are sampled and stored during sensing windows following R-wave and T-wave detections, respectively. ECG and heart sound data are stored in a continuous, looping memory, and segments of data are stored in long-term memory upon an automatic or manual data storage triggering event. Estimated blood pressure is calculated based on custom spectral analysis and processing of the first and second heart sounds. A calibration method includes measuring a patient's blood pressure using a standard clinical method and performing regression analysis on multiple spectral variables to identify a set of best fit weighted equations for predicting blood pressure. Concurrent ECG and estimated blood pressure may be displayed for review by a physician.

摘要翻译： 一种用于从心脏声音数据导出血压的微创植入式心音和ECG监测器及相关方法。 该装置配备有用于检测在R波和T波检测之后的感测窗口期间被采样和存储的第一和第二心音的声学传感器。 ECG和心音数据存储在连续的环路存储器中，并且数据段在自动或手动数据存储触发事件时存储在长期存储器中。 基于自定义频谱分析和第一和第二心脏声音的处理来计算估计的血压。 校准方法包括使用标准临床方法测量患者的血压并对多个光谱变量执行回归分析以识别用于预测血压的一组最佳拟合加权方程式。 并发ECG和估计的血压可能会被显示出来供医师审查。