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公开(公告)号:US20090324590A1
公开(公告)日:2009-12-31
申请号:US12376289
申请日:2007-08-02
申请人: Ravi Kambadur , Mridula Sharma , Monica Senna Salerno De Moura , Carole J. Berry , Victoria Siriett , Robert Syndecombe Bower , Gina Diane Nicholas , Craig Desmond McFarlane
发明人: Ravi Kambadur , Mridula Sharma , Monica Senna Salerno De Moura , Carole J. Berry , Victoria Siriett , Robert Syndecombe Bower , Gina Diane Nicholas , Craig Desmond McFarlane
IPC分类号: A61K39/395 , C07K14/435 , C07K16/00 , A61K38/16 , C12P21/06 , C07H21/04
CPC分类号: C07K14/475 , A61K38/00
摘要: An isolated recombinant polypeptide having myostatin antagonist activity, comprising a C-terminally truncated mature myostatin peptide, wherein the C-terminal truncation is at a position at or between amino acids 281 and 329, or a fragment, variant or derivative thereof.
摘要翻译: 一种具有肌肉生长抑制素拮抗剂活性的分离的重组多肽,其包含C-末端截短的成熟肌生成抑制素肽,其中C-末端截短位于氨基酸281和329之间或之间,或其片段,变体或衍生物。
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公开(公告)号:US08309068B2
公开(公告)日:2012-11-13
申请号:US12376289
申请日:2007-08-02
申请人: Ravi Kambadur , Mridula Sharma , Monica Senna Salerno De Moura , Carole J. Berry , Victoria Siriett , Robert Syndecombe Bower , Gina Diane Nicholas , Craig Desmond McFarlane
发明人: Ravi Kambadur , Mridula Sharma , Monica Senna Salerno De Moura , Carole J. Berry , Victoria Siriett , Robert Syndecombe Bower , Gina Diane Nicholas , Craig Desmond McFarlane
CPC分类号: C07K14/475 , A61K38/00
摘要: An isolated recombinant polypeptide having myostatin antagonist activity, comprising a C-terminally truncated mature myostatin peptide, wherein the C-terminal truncation is at a position at or between amino acids 281 and 329, or a fragment, variant or derivative thereof.
摘要翻译: 一种具有肌肉生长抑制素拮抗剂活性的分离的重组多肽,其包含C-末端截短的成熟肌生成抑制素肽,其中C-末端截短位于氨基酸281和329之间或之间,或其片段,变体或衍生物。
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