公开(公告)号：US20110291321A1

公开(公告)日：2011-12-01

申请号：US13207861

申请日：2011-08-11

申请人： Raymond CHAN ,  Robert MANZKE ,  Douglas A. STANTON ,  Guy SHECHTER

发明人： Raymond CHAN ,  Robert MANZKE ,  Douglas A. STANTON ,  Guy SHECHTER

IPC分类号： B29C39/10

CPC分类号： G09B23/32 ,  B29C33/3857 ,  B29C39/021 ,  B29C39/123 ,  B29C2033/3871 ,  B29K2029/04 ,  B29K2083/005 ,  B29L2031/753

摘要： A method, system and apparatus for manufacturing anatomically and functionally accurate soft tissue phantoms with multimodality characteristics for imaging studies is disclosed. The organ/tissue phantom is constructed by filling a container containing an organ having inner vasculature therein with a molten elastomeric material; inserting a plurality of rods with bumps thereupon through the container and the organ; allowing the molten elastomeric material to harden and cure; removing the organ; replacing the organ with a plurality of elastomeric segments; and removing an elastomeric segment and replacing the void created thereupon with molten PVA to create a PVA segment; allowing the molten PVA segment to harden and cure; and repeating the creation of PVA segments until all the elastomeric segments have been removed, such that each successive molten PVA segment adheres to and fuses with the previous hardened PVA segment so as to form an approximately complete organ phantom cast. The organ/tissue phantom is completed by inserting the approximately complete organ phantom cast inserting upside-down into a fixture made from the bottom-most elastomeric segment, which contains molten PVA; and allowing the molten PVA to harden and cure.

摘要翻译： 公开了一种用于制造具有用于成像研究的多模态特征的解剖学和功能上精确的软组织模体的方法，系统和装置。 器官/组织体模是通过将含有内部脉管系统的器官的容器用熔融的弹性材料填充而构成的; 在其上插入多个具有凸块的杆穿过容器和器官; 使熔融的弹性体材料硬化和固化; 去除器官 用多个弹性片段代替器官; 并除去弹性链段并用熔融的PVA代替其上产生的空隙以产生PVA链段; 使熔融的PVA段硬化和固化; 并重复创建PVA片段，直到所有的弹性体片段都被去除，使得每个连续的熔融PVA片段粘附并与先前硬化的PVA片段熔合，从而形成近似完整的器官体模。 通过将近似完整的器官体模插入插入由最下面的弹性片段制成的夹具中来完成器官/组织体模，所述夹具包含熔融的PVA; 并使熔融的PVA硬化和固化。