公开(公告)号：US09597290B2

公开(公告)日：2017-03-21

申请号：US14826684

申请日：2015-08-14

Applicant: Regents of the University of Minnesota

Inventor： Jian-Ping Wang ,  Claire Hovland ,  Timothy Bloomquist ,  Jing Ying

IPC: A61K9/14 ,  A61K47/02 ,  B22F9/12 ,  C23C14/35 ,  H01J37/34 ,  B22F9/04 ,  B01J2/02 ,  B22F1/00 ,  B01J2/04

CPC classification number: A61K9/14 ,  A61K47/02 ,  B01J2/02 ,  B01J2/04 ,  B22F1/0062 ,  B22F9/04 ,  B22F9/12 ,  B22F2202/05 ,  B22F2998/10 ,  B22F2999/00 ,  C22C2202/02 ,  C23C14/35 ,  H01J37/34 ,  B22F3/003

Abstract: Particle functionalization systems including one or more of: a target of a material; an energetic ion and/or electron source providing accelerated ions and electrons to the target; a potential that is applied to at least the target and that causes ions and/or electrons from the ionized gas to impact a surface of the target and release atoms of the material; at least one magnet providing a magnetic field that controls movement of the ions and electrons and nucleation, formation and growth of particles from the released atoms; and a particle collection device that collects particles, the collection device comprising a substrate and a polymeric functionalization coating disposed on the substrate, wherein particles impinge upon and form bonds with molecules of the functionalization coating. Methods of preparing functionalized particles, functionalized particle compositions, and kits including functionalized particles are also described.

公开(公告)号：US20150352210A1

公开(公告)日：2015-12-10

申请号：US14826684

申请日：2015-08-14

Applicant: Regents of the University of Minnesota

Inventor： Jian-Ping Wang ,  Claire Hovland ,  Timothy Bloomquist ,  Jing Ying

IPC: A61K47/02 ,  C23C14/35 ,  A61K9/14

CPC classification number: A61K9/14 ,  A61K47/02 ,  B01J2/02 ,  B01J2/04 ,  B22F1/0062 ,  B22F9/04 ,  B22F9/12 ,  B22F2202/05 ,  B22F2998/10 ,  B22F2999/00 ,  C22C2202/02 ,  C23C14/35 ,  H01J37/34 ,  B22F3/003

Abstract: Particle functionalization systems including one or more of: a target of a material; an energetic ion and/or electron source providing accelerated ions and electrons to the target; a potential that is applied to at least the target and that causes ions and/or electrons from the ionized gas to impact a surface of the target and release atoms of the material; at least one magnet providing a magnetic field that controls movement of the ions and electrons and nucleation, formation and growth of particles from the released atoms; and a particle collection device that collects particles, the collection device comprising a substrate and a polymeric functionalization coating disposed on the substrate, wherein particles impinge upon and form bonds with molecules of the functionalization coating. Methods of preparing functionalized particles, functionalized particle compositions, and kits including functionalized particles are also described.

Abstract translation: 颗粒功能化系统包括以下一种或多种：材料的目标; 能量离子和/或电子源，向靶提供加速的离子和电子; 至少应用于靶并且使离子和/或电子从电离气体撞击靶表面并释放材料原子的电位; 提供磁场的至少一个磁体，其控制离子和电子的运动以及颗粒从释放的原子的成核，形成和生长; 以及收集颗粒的颗粒收集装置，所述收集装置包括基材和设置在所述基材上的聚合物官能化涂层，其中颗粒侵入并与所述官能化涂层的分子形成键。 还描述了制备官能化颗粒的方法，官能化颗粒组合物和包括官能化颗粒的试剂盒。