公开(公告)号：US20230192709A1

公开(公告)日：2023-06-22

申请号：US18162127

申请日：2023-01-31

Applicant: Relay Therapeutics, Inc. ,  D.E. Shaw Research, LLC

Inventor： Bakary-Barry TOURÉ ,  Heike SCHOENHERR ,  Fabrizio GIORDANETTO ,  Demetri T. MOUSTAKAS ,  Bradi M. DUDSON

IPC: C07D487/04 ,  C07D491/048 ,  C07D498/22 ,  C07D487/22 ,  C07D498/02 ,  C07D519/00

CPC classification number: C07D487/04 ,  C07D491/048 ,  C07D498/22 ,  C07D487/22 ,  C07D498/02 ,  C07D519/00

Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of FGFR enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with FGFR signaling with the compounds and compositions of the disclosure.