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1.发明授权
公开(公告)号：US6083430A
公开(公告)日：2000-07-04
申请号：US642026
申请日：1996-04-29
申请人： Richard C. Fuisz , Garry L. Myers , Robert K. Yang , Mark R. Herman , Whitney S. Cavanagh , John R. Sisak , Andrea S. Brothers
发明人： Richard C. Fuisz , Garry L. Myers , Robert K. Yang , Mark R. Herman , Whitney S. Cavanagh , John R. Sisak , Andrea S. Brothers
IPC分类号： A61J3/02 , A61J1/00 , A61J7/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K9/50 , B01J2/00 , B01J2/02 , A61K9/14
CPC分类号： A61J1/00 , A61J7/0015 , A61K9/1688 , A61K9/1694 , A61K9/2081 , A61K9/2095 , A61K9/5026 , B01J2/00 , B01J2/02
摘要： The present invention is a process and apparatus for making a dosage unit by direct tableting of shearlite particles. The present invention also includes the dosage unit itself. Shearlite particles, which are prepared by subjecting a feedstock material to liquiflash processing, can be directly fed from a shearlite device to a tableting apparatus without the necessity of any intermediate steps or additional ingredients to facilitate flowability or tablet formation.
摘要翻译： 本发明是通过直接压片剪切碎片制造剂量单位的方法和装置。 本发明还包括剂量单位本身。 通过使原料进行液化处理制备的剪切剂颗粒可以从剪切装置直接进给到压片装置，而不需要任何中间步骤或附加成分来促进流动性或形成片剂。
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公开(公告)号：US5965164A
公开(公告)日：1999-10-12
申请号：US642027
申请日：1996-04-29
IPC分类号： A61J3/02 , A61J1/00 , A61J7/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K9/50 , B01J2/00 , B01J2/02 , A61K9/14
CPC分类号： A61J7/0023 , A61J1/00 , A61J7/0015 , A61J7/0046 , A61K9/1688 , A61K9/1694 , A61K9/2081 , A61K9/2095 , A61K9/5026 , B01J2/00 , B01J2/02
摘要： A recipient-dosage delivery system including shearlite particles of a bio-affecting agent for delivery to a recipient. The particles are provided in a metered dose and are packaged in a bi-functional vessel. The particles are produced under liquiflash conditions and exhibit sufficient flowability so as to allow administration of the metered dose to the recipient under the force of gravity.
摘要翻译： 受体剂量递送系统，其包括用于递送至接受者的生物影响剂的剪切碎片颗粒。 颗粒以计量剂量提供并且包装在双功能容器中。 颗粒在液化条件下产生并显示出足够的流动性，以便允许在重力作用下将计量剂量给予受体。
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