摘要:
An electrochemiluminescence cell comprising an electrode capable of inducing an electrochemiluminescence-active species to electrochemiluminesce. The electrode is preferably made of rhodium, iridium or an alloy of platinum, rhodium or iridium alloyed with an alloy material comprising a transition element. The electrode may be used as counter electrode and/or as a working electrode in the electrochemiluminescence cell. The cell preferably includes a counter electrode and a support attached to the counter electrode. The support comprises a transparent portion in optical registration with the working electrode. The counter electrode may include one or more field extending elements interposed between the transparent portion and the working electrode. The field extending element is preferably a ladder or a grid.
摘要:
An electrochemiluminescence cell comprising an electrode capable of inducing an electrochemiluminescence-active species to electrochemiluminesce. The electrode is preferably made of rhodium, iridium or an alloy of platinum, rhodium or iridium alloyed with an alloy material comprising a transition element. The electrode may be used as counter electrode and/or as a working electrode in the electrochemiluminescence cell. The cell preferably includes a counter electrode and a support attached to the counter electrode. The support comprises a transparent portion in optical registration with the working electrode. The counter electrode may include one or more field extending elements interposed between the transparent portion and the working electrode. The field extending element is preferably a ladder or a grid.
摘要:
A system and method for assessing the immunological status of one or more individuals in a patient population is presented. The method includes establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, each of said records including (1) current information from one or more assays for the presence of a biochemical, and (2) individual specific information comprising one or more of said individual's medical history, said individual's doctors' observations and historical, demographic, lifestyle, and familial information relating to said individual. The method further includes processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population; and using the said trends or patterns as part of a health care related decision making process.
摘要:
A system and method for assessing immunological status of individuals and populations is presented. The method includes establishing a database containing a plurality of records, each record containing information representative of the immune status of an individual, including (1) bioassay results, and (2) individual specific information such as, medical history, clinical observations and historical, demographic, lifestyle, and familial/genetic information. By processing the information trends and/or patterns are obtained correlating various variables in the records across an individual, population or sub-population. The identified trends and/or patterns can, for example, be used in health care related decision making. In exemplary embodiments such processing can include generating a set of correlations and for each correlation generating a set of explanatory or relevant hypotheses. Then, for example, each hypothesis can be automatically refuted or supported, to the extent possible. The identified correlations, their associated hypotheses and the results of such automated vetting can then be reported to a user.
摘要:
A system and method for assessing the immunological status of one or more individuals in a patient population is presented. The method includes establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, each of said records including (1) current information from one or more assays for the presence of a biochemical, and (2) individual specific information comprising one or more of said individual's medical history, said individual's doctors' observations and historical, demographic, lifestyle, and familial information relating to said individual. The method further includes processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population; and using the said trends or patterns as part of a health care related decision making process. In exemplary embodiments of the present invention, processing the information in the database includes generating a list of correlations between variables or fields in the database. The correlations in the list can be further refined automatically, and a set of hypotheses or literature citations can be linked to the final correlations. The correlations, the processing, their associated hypotheses can then be reported to a user or automatically fed into another system component to generate a medical or health related decision. In exemplary embodiments of the present invention, a first assay panel containing a plurality of cytokine assays can be administered and the results processed. Based on automatic analyses of the cytokine data, a second tier or set of assays can be run on the same individual. The cytokine assay results being used to inform the contents of a second assay panel.