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公开(公告)号：US20080039378A1
公开(公告)日：2008-02-14
申请号：US11781095
申请日：2007-07-20
申请人： Richard Graham , Walter Tien , Mayssa Attar , Rhett Schiffman , Aileen Morgan
发明人： Richard Graham , Walter Tien , Mayssa Attar , Rhett Schiffman , Aileen Morgan
CPC分类号： A61K38/13 , A61K9/0048 , A61K9/08 , A61K47/02 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/44
摘要： Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
摘要翻译： 本文公开了与环孢菌素相关的治疗方法，组合物和药物。
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公开(公告)号：US09561178B2
公开(公告)日：2017-02-07
申请号：US11781095
申请日：2007-07-20
CPC分类号： A61K38/13 , A61K9/0048 , A61K9/08 , A61K47/02 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/44
摘要： Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
摘要翻译： 本文公开了与环孢菌素相关的治疗方法，组合物和药物。
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公开(公告)号：US20080146497A1
公开(公告)日：2008-06-19
申请号：US11858200
申请日：2007-09-20
申请人： Richard S. Graham , Walter L. Tien , Mayssa Attar , Rhett Schiffman , Aileen Morgan , David A. Hollander
发明人： Richard S. Graham , Walter L. Tien , Mayssa Attar , Rhett Schiffman , Aileen Morgan , David A. Hollander
CPC分类号： A61K38/13 , A61K9/0048 , A61K47/10 , A61K47/26 , A61K47/38
摘要： Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
摘要翻译： 本文公开了与环孢菌素相关的治疗方法，组合物和药物。
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公开(公告)号：US20080207495A1
公开(公告)日：2008-08-28
申请号：US12035698
申请日：2008-02-22
申请人： Richard S. Graham , Walter L. Tien , Mayssa Attar , Rhett Schiffman , Michael E. Stern , Robin Sears , John G. Walt , Tamara Cassaro
发明人： Richard S. Graham , Walter L. Tien , Mayssa Attar , Rhett Schiffman , Michael E. Stern , Robin Sears , John G. Walt , Tamara Cassaro
CPC分类号： A61K38/13 , A61K9/0048 , A61K9/08 , A61K47/02 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/44
摘要： Disclosed herein are methods of treating ocular rosacea with cyclosporin A. Compositions and medicaments related thereto are also disclosed.
摘要翻译： 本文公开了用环孢菌素A治疗眼酒渣酒的方法。还公开了与其相关的组合物和药物。
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公开(公告)号：US20110294744A1
公开(公告)日：2011-12-01
申请号：US13115764
申请日：2011-05-25
申请人： Aileen Morgan , Anuradha Gore , Mayssa Attar
发明人： Aileen Morgan , Anuradha Gore , Mayssa Attar
CPC分类号： A61K38/13 , A61K9/0048 , A61K9/107 , A61K31/77 , A61K36/47 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/24 , A61K47/26 , A61K47/34 , A61K47/38 , A61K47/44 , A61K2300/00
摘要： Disclosed herein is a composition comprising cyclosporin A at a concentration between about 0.001% (w/v) and about 1.0% (w/v), a plant oil at a concentration between about 0.01% (w/v) and about 10% (w/v), and macrogol 15 hydroxystearate at a concentration between about 0.01% (w/v) and about 10% (w/v).
摘要翻译： 本文公开了包含浓度为约0.001％（w / v）至约1.0％（w / v）的环孢菌素A，浓度为约0.01％（w / v）至约10％ w / v）和大约0.01％（w / v）至约10％（w / v）之间的浓度的羟基硬脂酸镁。
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6.发明申请KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN 审中-公开用于治疗或预防眼痛的KETOROLAC TROMETHAMINE组合物公开(公告)号：US20110021595A1
公开(公告)日：2011-01-27
申请号：US12685074
申请日：2010-01-11
申请人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Shiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
发明人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Shiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
IPC分类号： A61K31/407 , A61P27/02
CPC分类号： A61K31/407
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises mixtures of carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye and improve visual acuity of the users.
摘要翻译： 本发明提供了含有有效量的酮咯酸的水性眼用溶液，其包含羧甲基纤维素在水溶液中的混合物，其中所述浓度的羧甲基纤维素被选择以提供眼睛中酮咯酸的增加的吸收并提高使用者的视力。
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公开(公告)号：US20120196913A1
公开(公告)日：2012-08-02
申请号：US13446870
申请日：2012-04-13
申请人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
发明人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
IPC分类号： A61K31/407 , A61P29/00 , A61P27/02
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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8.发明申请KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN 审中-公开用于治疗或预防眼痛的KETOROLAC TROMETHAMINE组合物公开(公告)号：US20130030032A1
公开(公告)日：2013-01-31
申请号：US13393739
申请日：2010-08-31
申请人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
发明人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
IPC分类号： A61K31/407 , A61P29/00 , A61P27/02
CPC分类号： A61K31/407 , A61K9/0048 , A61K9/08 , A61K31/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution which provides increased visual acuity in users and wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient which is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
摘要翻译： 本发明提供一种眼用水溶液，其包含有效量的酮咯酸，其在水溶液中包含羧甲基纤维素，其在使用者中提供增加的视力，并且其中选择所述羧甲基纤维素的浓度以提高酮咯酸在眼睛中的吸收 患者比具有相同浓度的酮咯酸的对比的水性酮咯酸眼科溶液的吸收大至少130％。
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公开(公告)号：US20110160271A1
公开(公告)日：2011-06-30
申请号：US12953622
申请日：2010-11-24
申请人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
发明人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
IPC分类号： A61K31/407 , A61P29/00 , A61P27/02
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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公开(公告)号：US07842714B2
公开(公告)日：2010-11-30
申请号：US12396131
申请日：2009-03-02
申请人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
发明人： Eldon Q. Farnes , Mayssa Attar , Rhett M. Schiffman , Chin-Ming Chang , Richard S. Graham , Devin F. Welty
IPC分类号： A61K31/407 , A61P27/02
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution having an effective amount of ketorolac which includes carboxymethyl cellulose in an aqueous solution wherein the concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
摘要翻译： 本发明提供了具有有效量的酮咯酸的水性眼用溶液，其包括在水溶液中的羧甲基纤维素，其中选择羧甲基纤维素的浓度以提高患者眼睛中酮咯酸的吸收增加至少为130％ 比吸收具有相同浓度的酮咯酸的对比的水性酮咯酸眼科溶液。
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