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    Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
    4.
    发明授权
    Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders 有权
    止血导管和治疗中风和其他小血管血栓栓塞障碍的方法

    公开(公告)号：US06685722B1

    公开(公告)日：2004-02-03

    申请号：US09437530

    申请日：1999-11-10

    申请人： Robert F. Rosenbluth ,  George R. Green, Jr. ,  Brian J. Cox ,  Thomas R. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti

    发明人： Robert F. Rosenbluth ,  George R. Green, Jr. ,  Brian J. Cox ,  Thomas R. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti

    IPC分类号： A61M2900

    CPC分类号： A61B17/22032 ,  A61B17/135 ,  A61B17/221 ,  A61B2017/22034 ,  A61B2017/22044 ,  A61B2017/22077 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61B2017/320716 ,  A61F2/013 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/008 ,  A61F2230/0091 ,  A61M2025/0042 ,  A61M2025/0183

    摘要： Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot.

    摘要翻译： 用于从血管中去除凝块或其他阻塞物（例如，血栓，血栓栓塞，动脉粥样硬化斑块的栓塞碎片，异物等）的系统和方法，快速交换微导管。 本发明特别可用于在脑卒中或脑缺血期间经皮去除血栓栓塞或其他来自脑小血管的阻塞物质。 在一些实施例中，本发明的止血栓塞导管可以在已经插入穿过凝块或围绕凝块的导丝上或之上前进。 此外，在一些实施例中，止血管切除导管包括在导管至少部分地穿过血块前进之后可从导管展开的凝块移除装置。 凝块移除装置可以包括被设计成防止血块从其中通过的可展开的线巢。 输送导管可以包括伸缩的内管和外管，其中血块去除装置由外管径向约束。 外管的收缩消除了对凝块去除装置的约束，并允许其扩展到其部署构型。 输注导丝特别适用于结肠切除术导管，并且可以输送远离凝块的药物或可视化液体。

    Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
    5.
    发明授权
    Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders 有权
    止血导管和治疗中风和其他小血管血栓栓塞障碍的方法

    公开(公告)号：US08100935B2

    公开(公告)日：2012-01-24

    申请号：US11773601

    申请日：2007-07-05

    申请人： Robert F. Rosenbluth ,  George R. Green, Jr. ,  Brian J. Cox ,  Thomas R. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti

    发明人： Robert F. Rosenbluth ,  George R. Green, Jr. ,  Brian J. Cox ,  Thomas R. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti

    IPC分类号： A61M29/00

    CPC分类号： A61B17/22032 ,  A61B17/135 ,  A61B17/221 ,  A61B2017/22034 ,  A61B2017/22044 ,  A61B2017/22077 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61B2017/320716 ,  A61F2/013 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/008 ,  A61F2230/0091 ,  A61M2025/0042 ,  A61M2025/0183

    摘要： Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot.

    摘要翻译： 用于从血管中去除凝块或其他阻塞物（例如，血栓，血栓栓塞，动脉粥样硬化斑块的栓塞碎片，异物等）的系统和方法，快速交换微导管。 本发明特别可用于在脑卒中或脑缺血期间经皮去除血栓栓塞或其他来自脑小血管的阻塞物质。 在一些实施例中，本发明的止血栓塞导管可以在已经插入穿过凝块或围绕凝块的导丝上或之上前进。 此外，在一些实施例中，止血管切除导管包括在导管至少部分地穿过血块前进之后可从导管展开的凝块移除装置。 凝块移除装置可以包括被设计成防止血块从其中通过的可展开的线巢。 输送导管可以包括伸缩的内管和外管，其中血块去除装置由外管径向约束。 外管的收缩消除了对凝块去除装置的约束，并允许其扩展到其部署构型。 输注导丝特别适用于结肠切除术导管，并且可以输送远离凝块的药物或可视化液体。

    Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
    6.
    发明授权
    Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders 有权
    止血导管和治疗中风和其他小血管血栓栓塞障碍的方法

    公开(公告)号：US07691121B2

    公开(公告)日：2010-04-06

    申请号：US10730860

    申请日：2003-12-09

    申请人： Robert F. Rosenbluth ,  George R. Green, Jr. ,  Brian J. Cox ,  Thomas R. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti

    发明人： Robert F. Rosenbluth ,  George R. Green, Jr. ,  Brian J. Cox ,  Thomas R. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti

    IPC分类号： A61M29/00

    CPC分类号： A61B17/22032 ,  A61B17/135 ,  A61B17/221 ,  A61B2017/22034 ,  A61B2017/22044 ,  A61B2017/22077 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61B2017/320716 ,  A61F2/013 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/008 ,  A61F2230/0091 ,  A61M2025/0042 ,  A61M2025/0183

    摘要： Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may included a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot.

    摘要翻译： 用于从血管中去除凝块或其他阻塞物（例如，血栓，血栓栓塞，动脉粥样硬化斑块的栓塞碎片，异物等）的系统和方法，快速交换微导管。 本发明特别可用于在脑卒中或脑缺血期间经皮去除血栓栓塞或其他来自脑小血管的阻塞物质。 在一些实施例中，本发明的止血栓塞导管可以在已经插入穿过凝块或围绕凝块的导丝上或之上前进。 此外，在一些实施例中，止血管切除导管包括在导管至少部分地穿过血块前进之后可从导管展开的凝块移除装置。 凝块移除装置可以包括设计成防止血块从其中通过的可展开的线窝。 输送导管可以包括伸缩的内管和外管，其中血块去除装置由外管径向约束。 外管的收缩消除了对凝块去除装置的约束，并允许其扩展到其部署构型。 输注导丝特别适用于结肠切除术导管，并且可以输送远离凝块的药物或可视化液体。

    Miniaturized medical brush
    7.
    发明授权
    Miniaturized medical brush 有权
    小型医用刷

    公开(公告)号：US6030397A

    公开(公告)日：2000-02-29

    申请号：US217785

    申请日：1998-12-21

    申请人： Richard R. Monetti ,  Robert A. Pecor ,  Thomas R. Sternweiler ,  Brian M. Strauss

    发明人： Richard R. Monetti ,  Robert A. Pecor ,  Thomas R. Sternweiler ,  Brian M. Strauss

    IPC分类号： A61B17/22 ,  A61B17/32 ,  A61B17/00

    CPC分类号： A61B17/320758 ,  A61B2017/320012 ,  A61B2017/320733

    摘要： A miniaturized brush particularly adapted for medical use formed at the distal end of an elongated brush drive shaft having a hollow lumen formed therein for introduction over a guidewire. The brush drive shaft is enclosed in the lumen of a brush delivery catheter and other components of a brush sub-assembly adapted to deliver infusate through the catheter lumen and to be coupled to a drive motor unit for rotating the brush drive shaft and brush. The brush bristles of the distal brush are adapted to be garaged in a distal end section of the brush delivery catheter lumen during introduction through a body lumen. The brush bristles are formed of a thin sheet of rigid plastic material that is shaped to have a plurality of fringe elements extending in parallel from a mounting web. The mounting web is wound about and attached to a distal end section of the drive shaft outer circumference so that the fringe elements extend outward from the drive shaft surface and obliquely of the drive shaft axis. Preferably, proximal and distal spiral brush sections are formed in this manner so that fluids are impelled distally and proximally, respectively, between the proximal and distal brush sections as infusate is delivered.

    摘要翻译： 一种特别适用于医疗用途的微型电刷，形成在细长刷驱动轴的远端，其具有形成在其中的中空腔，用于引导导丝。 电刷驱动轴被封闭在电刷输送导管的内腔中，并且刷子子组件的其它部件适于通过导管管腔传送输液，并且连接到用于旋转刷驱动轴和刷子的驱动马达单元。 远端刷的刷毛适于在通过体腔的引入期间被储存在刷递送导管腔的远端部分中。 刷毛由一片刚性塑料材料制成，其形状为具有从安装幅材平行延伸的多个边缘元件。 安装网缠绕并附接到驱动轴外周的远端部分，使得边缘元件从驱动轴表面向外延伸并且驱动轴轴线倾斜。 优选地，以这种方式形成近端螺旋刷部分和远端螺旋刷部分，使得流体在分泌物输送时在近端和远端刷部分之间分别向远侧和近侧推进。

    Endovascular catheter resheathing apparatus and related methods
    8.
    发明授权
    Endovascular catheter resheathing apparatus and related methods 有权
    血管内导管再手术装置及相关方法

    公开(公告)号：US07048719B1

    公开(公告)日：2006-05-23

    申请号：US10165103

    申请日：2002-06-07

    申请人： Richard R. Monetti

    发明人： Richard R. Monetti

    IPC分类号： A61M5/00

    CPC分类号： A61M25/0668

    摘要： A resheathing apparatus for a tube that is insertable through an endovascular catheter includes a guide that has a proximal end, a distal end, at least one lumen extending from the proximal end to the distal end, and a branch extending away from the lumen at one end of the guide. A sheath may be placed over the tube by sliding the resheathing apparatus along the length of the tube. The resheathing apparatus may also include a guide tube that fits over the branch of the guide and directs a sheath over the tube that is insertable through an endovascular catheter. The resheathing apparatus may be used with vascular embolization devices, and may be used with devices that are delivered via microcatheter systems. Methods of using the resheathing apparatus are also disclosed.

    摘要翻译： 用于可插入通过血管内导管的管的再适应装置包括具有近端，远端，至少一个从近端延伸到远端的腔的引导件，以及在一端延伸远离内腔的分支 指南结束。 可以通过沿着管的长度滑动再凝固装置将护套放置在管上。 再过硫化装置还可以包括引导管，该引导管装配在引导件的分支上方，并将护套引导到可插入血管内导管的管上。 再凝固装置可用于血管栓塞装置，并且可以与通过微导管系统递送的装置一起使用。 还公开了使用再湿化装置的方法。