公开(公告)号：US06613351B1

公开(公告)日：2003-09-02

申请号：US09150976

申请日：1998-09-11

Applicant: Jean-Marie Ruysschaert ,  Robert Fuks ,  Michel Vandenbranden

Inventor： Jean-Marie Ruysschaert ,  Robert Fuks ,  Michel Vandenbranden

IPC: A61K9127

CPC classification number: C12N15/88 ,  A61K9/1272 ,  A61K47/543 ,  A61K47/6907 ,  A61K48/00 ,  C07C257/06 ,  C07C257/14 ,  C12N15/8206 ,  C12N15/87

Abstract: The invention includes a vector including a complex between at least one compound having an amidine polar head of formula where m is 14 and at least one of nucleic acids molecules, polypeptides, and glycosylated polypeptides.

Abstract translation: 本发明包括载体，其包含至少一种具有缬氨酸的脒极性头的化合物之间的复合物，其为14和至少一种核酸分子，多肽和糖基化多肽。

公开(公告)号：US3954863A

公开(公告)日：1976-05-04

申请号：US358357

申请日：1973-05-08

Applicant: Robert Fuks

Inventor： Robert Fuks

IPC: C08F26/02 ,  C07C123/00

CPC classification number: C08F26/02 ,  Y10S526/923

Abstract: N-substituted acrylamidines, a new class of acrylic monomers, are synthesized by the process of this invention which comprises successively contacting with an acrylonitrile or derivative thereof (a) a Lewis acid catalyst, (b) an alkyl halide and (c) an amine. Novel polyacrylamidines as well as quaternary salts of polyacrylamidines are disclosed. Due to their basic nature the N-substituted acrylamidines are useful for introducing basic groups into polymers.

Abstract translation: 通过本发明的方法合成N-取代的丙烯酰胺，一类新的丙烯酸类单体，其包括与丙烯腈或其衍生物（a）路易斯酸催化剂，（b）烷基卤和（c）胺 。 公开了新型聚丙烯酰胺和聚丙烯酰胺的季盐。 由于其基本性质，N-取代的丙烯酰胺可用于将碱性基团引入聚合物。