Bipolar cardiac lead with drug eluting device
    1.
    发明授权
    Bipolar cardiac lead with drug eluting device 失效
    双极心脏铅与药物洗脱装置

    公开(公告)号:US5217028A

    公开(公告)日:1993-06-08

    申请号:US912321

    申请日:1992-07-13

    IPC分类号: A61N1/05 A61N1/375

    CPC分类号: A61N1/375 A61N1/0587

    摘要: A bi-polar cardiac lead for transmitting electric current to the heart and/or sensing and monitoring electrical activity of the heart has elongated electrical conductors connected to a head. The lead has a first electrode mounted on the head having a helical wire connected to one conductor adapted to be turned into heart tissue. The helical wire is coated with platinum black particles which decrease electrical losses at the electrode-tissue interface. A second annular electrode having an irregular outer surface configuration is mounted on the head around the first electrode. A plug impregnated with a drug is located within a recess in the head adjacent the electrodes. The drug migrates from the plug to the stimulation site.

    摘要翻译: 用于将电流传输到心脏和/或感测和监测心脏的电活动的双极心脏引线具有连接到头部的细长电导体。 引线具有安装在头部上的第一电极,其具有连接到适于被转换成心脏组织的一个导体的螺旋线。 螺旋线涂有白金黑色颗粒,减少电极 - 组织界面处的电损耗。 具有不规则外表面构造的第二环形电极安装在围绕第一电极的磁头上。 浸渍有药物的塞子位于与电极相邻的头部的凹部内。 药物从塞子迁移到刺激部位。

    Cardiac lead
    2.
    发明授权
    Cardiac lead 失效
    心脏导联

    公开(公告)号:US5255693A

    公开(公告)日:1993-10-26

    申请号:US896663

    申请日:1992-06-10

    IPC分类号: A61N1/05 A61N1/375

    CPC分类号: A61N1/0587 A61N1/375

    摘要: A cardiac lead for transmitting electric current to the heart and/or sensing and monitoring electrical activity of the heart has an elongated electrical conductor connected to a head. An electrode mounted on the head comprises a helical wire adapted to be turned into heart tissue. The helical wire is coated with platinum black particles which decrease electrical losses at the electrode-tissue interface. A plug impregnated with a drug located within the head is in contact with the helical wire and platinum black particles thereon. The drug migrates from the plug to the active outer end section of the electrode.

    摘要翻译: 用于将电流传输到心脏和/或感测和监测心脏的电活动的心脏引线具有连接到头部的细长电导体。 安装在头部上的电极包括适于变成心脏组织的螺旋线。 螺旋线涂有白金黑色颗粒,减少电极 - 组织界面处的电损耗。 浸渍在头部内的药物的塞子与其上的螺旋丝和铂黑粒子接触。 药物从塞子迁移到电极的活性外端部分。

    Cardiac lead
    3.
    发明授权
    Cardiac lead 失效
    心脏导联

    公开(公告)号:US5143090A

    公开(公告)日:1992-09-01

    申请号:US707681

    申请日:1991-05-30

    IPC分类号: A61N1/05 A61N1/375

    CPC分类号: A61N1/375 A61N1/0587

    摘要: A cardiac lead for transmitting electric current to the heart and/or sensing and monitoring electrical activity of the heart has an elongated electrical conductor connected to a head. An electrode mounted on the head comprises a helical wire adapted to be turned into heart tissue. A second electrode having an irregular or non-flat surface surrounds the helical wire. The non-flat surface may be a wire mesh, a segmented plate and an annular plate supporting one or more coiled wires.

    摘要翻译: 用于将电流传输到心脏和/或感测和监测心脏的电活动的心脏引线具有连接到头部的细长电导体。 安装在头部上的电极包括适于变成心脏组织的螺旋线。 具有不规则或非平坦表面的第二电极围绕螺旋线。 非平坦表面可以是金属丝网,分段板和支撑一个或多个螺旋线的环形板。

    Releasable lock assembly
    5.
    发明授权
    Releasable lock assembly 失效
    可释放锁组件

    公开(公告)号:US5040545A

    公开(公告)日:1991-08-20

    申请号:US600627

    申请日:1990-10-22

    IPC分类号: A61N1/05 A61N1/375

    摘要: A tool for implanting a pacing lead into heart tissue has a pair of side-by-side beams pivoted together at the opposite ends thereof. The beams have jaws that grip a lead head supporting a helical electrode and a groove for accommodating a section of the lead extended from the head. A releasable lock interposed between the beams operates to hold the beams in jaw closed position to grip the head of the electrode. the lock has flexible fingers and a movable sleeve that allows one hand operation to selectively lock and release of the jaws. The helical electrode has an external layer of platinum black particles resulting in decreased electrical losses at the electrode-tissue interface, increased current density, lower stimulation thresholds, and increased amplitude of sensed electrical signals from the heart tissue.

    摘要翻译: 用于将起搏引线植入心脏组织的工具具有在其相对端枢转在一起的一对并排梁。 梁具有夹持支撑螺旋电极的引导头和用于容纳从头部延伸的引线的一部分的凹槽的钳口。 插入在梁之间的可释放的锁操作以将梁保持在闭合位置以夹紧电极的头部。 锁具有柔性指状物和可移动套筒,其允许单手操作来选择性地锁定和释放钳口。 螺旋电极具有铂黑色颗粒的外层,导致电极 - 组织界面处的电损耗降低,电流密度增加,刺激阈值增加,并且来自心脏组织的感测电信号的幅度增加。

    Pacing lead and introducer therefor
    6.
    发明授权
    Pacing lead and introducer therefor 失效
    起搏线及导引器

    公开(公告)号:US4972847A

    公开(公告)日:1990-11-27

    申请号:US430596

    申请日:1989-11-02

    IPC分类号: A61N1/05 A61N1/372 A61N1/375

    CPC分类号: A61N1/0587 A61N1/375

    摘要: A tool for implanting a pacing lead into heart tissue has a pair of side-by-side beams pivoted together at the opposite ends thereof. The beams have jaws that grip a lead head supporting a helical electrode and a groove for accommodating a section of the lead extended from the head. A releasable lock interposed between the beams operates to hold the beams in jaw closed position to grip the head of the electrode. The lock has flexible fingers and a movable sleeve that allows one hand operation to selectively lock and release of the jaws. The helical electrode has an external layer of platinum black particles resulting in decreased electrical losses at the electrode-tissue interface, increased current density, lower stimulation thresholds, and increased amplitude of sensed electrical signals from the heart tissue.

    摘要翻译: 用于将起搏引线植入心脏组织的工具具有在其相对端枢转在一起的一对并排梁。 梁具有夹持支撑螺旋电极的引导头和用于容纳从头部延伸的引线的一部分的凹槽的钳口。 插入在梁之间的可释放的锁操作以将梁保持在闭合位置以夹紧电极的头部。 锁具有柔性指状物和可移动套筒,其允许单手操作来选择性地锁定和释放钳口。 螺旋电极具有铂黑色颗粒的外层,导致电极 - 组织界面处的电损耗降低,电流密度增加,刺激阈值增加,并且来自心脏组织的感测电信号的幅度增加。

    Cardiac lead with retractible fixators
    7.
    发明授权
    Cardiac lead with retractible fixators 失效
    CARDIAC引线与可复位固定器

    公开(公告)号:US5179962A

    公开(公告)日:1993-01-19

    申请号:US718377

    申请日:1991-06-20

    IPC分类号: A61N1/05

    CPC分类号: A61N1/0573

    摘要: A cardiac lead has an electrode and fixation assembly including a plurality of fixation members movable to extended positions into heart tissue to retain the electrode in intimate engagement with heart tissue. An elongated stylet is used to move the fixation members to their extended positions into the heart tissue and retract the fixation members into the fixation assembly to allow the lead to be removed from the heart and body of a person.

    摘要翻译: 心脏引线具有电极和固定组件,其包括可移动到延伸位置进入心脏组织的多个固定构件,以将电极保持与心脏组织的紧密接合。 细长的探针用于将固定构件移动到其延伸位置进入心脏组织,并将固定构件缩回到固定组件中,以允许导线从人的心脏和身体移除。

    Thrombectomy method
    8.
    发明授权
    Thrombectomy method 失效
    血栓切除术

    公开(公告)号:US06558366B1

    公开(公告)日:2003-05-06

    申请号:US08349665

    申请日:1994-12-05

    IPC分类号: A61M3100

    CPC分类号: A61B17/32037 A61B17/3203

    摘要: A method of and apparatus for removing a thrombus deposit from the cardiovascular system of a patient without the need to surgically access the location of the thrombus deposit via a cut-down or other surgical procedure. A catheter is inserted percutaneously into the patient at a convenient location either directly or over a previously positioned guide wire. The distal end of the catheter is advanced under fluoroscopy to the site of the thrombus deposit. A balloon is inflated to stabilize the position of the distal end of the catheter within the center of the vessel lumen. A flexible metal tube conveys an extremely high pressure stream of sterile saline solution to at least one jet at the distal end of the catheter. At least one jet positions the thrombus deposit for emulsification by at least one other jet. By directing the jets toward the orifice of the large evacuation lumen of the catheter, a stagnation pressure is induced which propels the emulsion proximally for disposal. The rate of proximal flow of effluent is metered to correspond with the distal flow of saline solution to ensure minimal local impact on the vasculature at the site of the thrombus deposit.

    摘要翻译: 一种用于从患者的心血管系统中去除血栓沉积物的方法和装置,而不需要通过切割或其它外科手术手术地进入血栓沉积物的位置。 在方便的位置,将导管经皮插入患者中,直接或超过预先定位的导丝。 导管的远端在荧光透视下前进到血栓沉积部位。 气囊膨胀以将导管的远端的位置稳定在血管内腔的中心内。 柔性金属管将非常高压的无菌盐水溶液流传送到导管远端处的至少一个射流。 至少一个喷射器通过至少一个其它喷射器将血栓沉积物定位成乳化。 通过将射流引导到导管的大抽空腔的孔口,引起停滞压力,其推动乳剂向近端处理。 流出物的近端流量计量以与盐溶液的远端流动相对应,以确保对血栓沉积部位的脉管系统的局部影响最小。

    Thrombectomy and tissue removal device
    9.
    发明授权
    Thrombectomy and tissue removal device 失效
    血栓切除术和组织清除装置

    公开(公告)号:US6096001A

    公开(公告)日:2000-08-01

    申请号:US351616

    申请日:1994-12-08

    CPC分类号: A61B17/32037 A61B17/3203

    摘要: A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one jet at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet(s) is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet(s) can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness. The rate of exhaust of tissue debris is metered to ensure minimal local impact on the vasculature at the site of the thrombus deposit. A fluid metering means, such as a roller pump, controls the rate of exhaust such that it is in balance with the saline input or can be adjusted to be greater or less than the input. A positive displacement pump operating at steady or pulsatile flow provides the high pressure saline to the tip of the catheter.

    摘要翻译: 一种用于从心血管系统去除血栓或其他组织沉积物的装置,在患者的人体中发现的天然或合成的小管或腔,而不需要经由切口或外科手术来进入血栓或其他组织沉积物的位置 其他外科手术。 柔性金属或高压塑料管将非常高压的无菌盐水或其他生理溶液流输送到导管远端处的至少一个射流。 至少一个射流指向大排气腔或其他靶的开口。 喷气机负责提供局部的负压,其将组织夹带到喷射器中从碎片的分解中。 这种喷射器还可以在排气腔中提供停滞压力,其将组织或血栓形成的碎片驱动出排出管腔。 尖端压力大于500 psi的设备的操作为该设备提供了有助于其有效性的夹带和排气特性。 计量组织碎片的排气速率,以确保局部对血栓沉积部位脉管系统的局部影响最小。 诸如辊式泵的流体计量装置控制排气速率,使其与盐水输入平衡,或者可以将其调节为大于或小于输入。 以稳定或脉动流动运行的容积式泵向导管的尖端提供高压盐水。