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公开(公告)号:US07521441B2
公开(公告)日:2009-04-21
申请号:US11745090
申请日:2007-05-07
申请人: Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
发明人: Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
IPC分类号: A61P31/00 , A61K31/407 , C07D487/00
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US20070270406A1
公开(公告)日:2007-11-22
申请号:US11745090
申请日:2007-05-07
申请人: Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
发明人: Robert G. Gentles , Piyasena Hewawasam , Min Ding , Carl P. Bergstrom , Scott W. Martin , Kap-Sun Yeung , Thomas W. Hudyma , Xiaofan Zheng , John A. Bender , John F. Kadow
IPC分类号: A61K31/55 , C07D487/04
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07473688B2
公开(公告)日:2009-01-06
申请号:US11516435
申请日:2006-09-06
申请人: Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
发明人: Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
IPC分类号: A61K31/55 , A61P31/00 , C07D223/14
CPC分类号: C07D491/14 , C07D487/04
摘要: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I,II,III和IV的化合物和盐以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07547690B2
公开(公告)日:2009-06-16
申请号:US12039239
申请日:2008-02-28
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D519/00 , C07D487/04
摘要: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物,包括药学上可接受的盐,以及使用这些化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07541353B2
公开(公告)日:2009-06-02
申请号:US12045874
申请日:2008-03-11
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US20080227769A1
公开(公告)日:2008-09-18
申请号:US12039239
申请日:2008-02-28
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61K31/397 , C07D223/14 , A61P31/12 , A61K31/55
CPC分类号: C07D519/00 , C07D487/04
摘要: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物,包括药学上可接受的盐,以及使用这些化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US20080226591A1
公开(公告)日:2008-09-18
申请号:US12045874
申请日:2008-03-11
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61K31/55 , C07D487/04 , A61K38/21 , C07D491/08 , A61K38/20 , C07D471/04
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US07399758B2
公开(公告)日:2008-07-15
申请号:US11507731
申请日:2006-08-22
申请人: Nicholas A. Meanwell , Robert G. Gentles , Min Ding , John A. Bender , John F. Kadow , Piyasena Hewawasam , Thomas W. Hudyma , Xiaofan Zheng
发明人: Nicholas A. Meanwell , Robert G. Gentles , Min Ding , John A. Bender , John F. Kadow , Piyasena Hewawasam , Thomas W. Hudyma , Xiaofan Zheng
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I的化合物,其药学上可接受的盐,组合物和使用该化合物的方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07485633B2
公开(公告)日:2009-02-03
申请号:US11684710
申请日:2007-03-12
申请人: Nicholas A. Meanwell , Robert G. Gentles , Min Ding , John A. Bender , John F. Kadow , Piyasena Hewawasam , Thomas W. Hudyma , Xiaofan Zheng
发明人: Nicholas A. Meanwell , Robert G. Gentles , Min Ding , John A. Bender , John F. Kadow , Piyasena Hewawasam , Thomas W. Hudyma , Xiaofan Zheng
IPC分类号: A61K31/55 , A61P31/00 , C07D223/14
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I的化合物,其药学上可接受的盐,组合物和使用该化合物的方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07538102B2
公开(公告)日:2009-05-26
申请号:US12046030
申请日:2008-03-11
申请人: Kap-Sun Yeung , John A. Bender , Robert G. Gentles , Zhong Yang , Min Ding , Yong Tu , Piyasena Hewawasam , Ying Han , John F. Kadow
发明人: Kap-Sun Yeung , John A. Bender , Robert G. Gentles , Zhong Yang , Min Ding , Yong Tu , Piyasena Hewawasam , Ying Han , John F. Kadow
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04 , C07D519/00
摘要: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I的化合物,其药学上可接受的盐,组合物和使用该化合物的方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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