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公开(公告)号:US07538102B2
公开(公告)日:2009-05-26
申请号:US12046030
申请日:2008-03-11
申请人: Kap-Sun Yeung , John A. Bender , Robert G. Gentles , Zhong Yang , Min Ding , Yong Tu , Piyasena Hewawasam , Ying Han , John F. Kadow
发明人: Kap-Sun Yeung , John A. Bender , Robert G. Gentles , Zhong Yang , Min Ding , Yong Tu , Piyasena Hewawasam , Ying Han , John F. Kadow
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04 , C07D519/00
摘要: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I的化合物,其药学上可接受的盐,组合物和使用该化合物的方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US20080226592A1
公开(公告)日:2008-09-18
申请号:US12046030
申请日:2008-03-11
申请人: Kap-Sun Yeung , John A. Bender , Robert G. Gentles , Zhong Yang , Min Ding , Yong Tu , Piyasena Hewawasam , Ying Han , John F. Kadow
发明人: Kap-Sun Yeung , John A. Bender , Robert G. Gentles , Zhong Yang , Min Ding , Yong Tu , Piyasena Hewawasam , Ying Han , John F. Kadow
IPC分类号: A61K31/55 , C07D487/04 , A61P31/12 , A61K38/21 , A61K38/20
CPC分类号: C07D487/04 , C07D519/00
摘要: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I的化合物,其药学上可接受的盐,组合物和使用该化合物的方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07547690B2
公开(公告)日:2009-06-16
申请号:US12039239
申请日:2008-02-28
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D519/00 , C07D487/04
摘要: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物,包括药学上可接受的盐,以及使用这些化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US07541353B2
公开(公告)日:2009-06-02
申请号:US12045874
申请日:2008-03-11
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US20080227769A1
公开(公告)日:2008-09-18
申请号:US12039239
申请日:2008-02-28
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61K31/397 , C07D223/14 , A61P31/12 , A61K31/55
CPC分类号: C07D519/00 , C07D487/04
摘要: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译: 本发明包括式I化合物,包括药学上可接受的盐,以及使用这些化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US20080226591A1
公开(公告)日:2008-09-18
申请号:US12045874
申请日:2008-03-11
申请人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人: Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号: A61K31/55 , C07D487/04 , A61K38/21 , C07D491/08 , A61K38/20 , C07D471/04
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US07521444B2
公开(公告)日:2009-04-21
申请号:US12045766
申请日:2008-03-11
申请人: John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
发明人: John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
IPC分类号: A61P31/00 , A61K31/55 , C07D223/14
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US20080226590A1
公开(公告)日:2008-09-18
申请号:US12045766
申请日:2008-03-11
申请人: John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
发明人: John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
IPC分类号: A61K31/55 , C07D487/04 , A61P31/12 , A61K38/20 , A61K38/21 , C07D471/04
CPC分类号: C07D487/04
摘要: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号:US08293909B2
公开(公告)日:2012-10-23
申请号:US12720182
申请日:2010-03-09
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: C07D471/04 , A61K31/437
CPC分类号: C07D209/42 , C07D333/68 , C07D471/04 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号:US20100249094A1
公开(公告)日:2010-09-30
申请号:US12721423
申请日:2010-03-10
申请人: Kap-Sun Yeung , Kyle E. Parcella , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , John F. Kadow , Andrew Nickel
发明人: Kap-Sun Yeung , Kyle E. Parcella , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , John F. Kadow , Andrew Nickel
IPC分类号: A61K31/343 , C07D307/68 , C07D405/12 , C07D417/14 , C07D413/12 , C07D491/06 , A61K31/551 , A61K31/5377 , A61K31/496 , A61K31/4525 , A61K31/506 , A61K31/397 , A61K31/427 , A61K31/443 , A61K31/497 , A61K31/4155 , A61P31/12
CPC分类号: A61K31/506 , A61K45/06 , C07D307/84 , C07D405/04 , C07D405/10 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/10 , C07D413/12 , C07D417/10 , C07D417/12 , C07D453/00 , C07D491/10
摘要: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译: 本公开提供式I化合物,包括其盐,以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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