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公开(公告)号：US08282930B2
公开(公告)日：2012-10-09
申请号：US12679519
申请日：2008-09-24
CPC分类号： A61K31/683 , A61K9/127 , A61K9/1277 , A61K31/685 , A61K38/177 , A61K47/6919 , A61K47/6925 , A61K49/0043 , A61K49/008
摘要： An isolated caveolin containing vesicle comprising a caveolin protein and at least one lipid, wherein at least about 30% of the at least one lipid is selected from phosphatidylethanolamine and phosphatidylglycerol is disclosed. Also disclosed is a method of making an isolated caveolin containing vesicle, an isolated caveolin containing vesicle comprising a recombinant caveolin protein, an isolated caveolin containing delivery vesicle, a method of making an isolated caveolin containing delivery vesicle and a method of treatment of a disease or condition by delivery of a molecule using the isolated caveolin containing delivery vesicle.
摘要翻译： 包含含有窖蛋白和至少一种脂质的分离的含有小窝蛋白的囊泡，其中至少一种脂质的至少约30％选自磷脂酰乙醇胺和磷脂酰甘油。 还公开了制备含有囊泡的分离的小窝蛋白的方法，含有重组窖蛋白的分离的含窖蛋白的囊泡，含有分离的含窖蛋白的递送囊泡，分离的含有小窝蛋白的分泌小泡的方法，以及治疗疾病的方法或 通过使用分离的含窖蛋白的递送囊泡递送分子的条件。
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公开(公告)号：US20100267846A1
公开(公告)日：2010-10-21
申请号：US12679519
申请日：2008-09-24
CPC分类号： A61K31/683 , A61K9/127 , A61K9/1277 , A61K31/685 , A61K38/177 , A61K47/6919 , A61K47/6925 , A61K49/0043 , A61K49/008
摘要： An isolated caveolin containing vesicle comprising a caveolin protein and at least one lipid, wherein at least about 30% of the at least one lipid is selected from phosphatidylethanolamine and phosphatidylglycerol is disclosed. Also disclosed is a method of making an isolated caveolin containing vesicle, an isolated caveolin containing vesicle comprising a recombinant caveolin protein, an isolated caveolin containing delivery vesicle, a method of making an isolated caveolin containing delivery vesicle and a method of treatment of a disease or condition by delivery of a molecule using the isolated caveolin containing delivery vesicle.
摘要翻译： 包含含有窖蛋白和至少一种脂质的分离的含有小窝蛋白的囊泡，其中至少一种脂质的至少约30％选自磷脂酰乙醇胺和磷脂酰甘油。 还公开了制备含有囊泡的分离的小窝蛋白的方法，含有重组窖蛋白的分离的含窖蛋白的囊泡，含有分离的含窖蛋白的递送囊泡，分离的含有小窝蛋白的分泌小泡的方法，以及治疗疾病的方法或 通过使用分离的含窖蛋白的递送囊泡递送分子的条件。
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