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公开(公告)号:US20050164928A1
公开(公告)日:2005-07-28
申请号:US10953902
申请日:2004-09-27
申请人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
发明人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
CPC分类号: A61K38/57
摘要: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译: 描述了用于预防或减少患者中局部缺血,例如脑缺血和/或再灌注损伤(例如与脑缺血相关的再灌注损伤)的方法。
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公开(公告)号:US20070049522A1
公开(公告)日:2007-03-01
申请号:US11466979
申请日:2006-08-24
申请人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
发明人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
IPC分类号: A61K38/55
CPC分类号: A61K38/57
摘要: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译: 描述了用于预防或减少患者中局部缺血,例如脑缺血和/或再灌注损伤(例如与脑缺血相关的再灌注损伤)的方法。
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公开(公告)号:US20080076712A1
公开(公告)日:2008-03-27
申请号:US11929729
申请日:2007-10-30
申请人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号: A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
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公开(公告)号:US20070249807A1
公开(公告)日:2007-10-25
申请号:US11323261
申请日:2005-12-30
申请人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号: C07K14/8114 , C07K14/8121
摘要: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译: 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法,例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术,特别是当此类手术涉及体外循环,如体外循环时。
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公开(公告)号:US20060194727A1
公开(公告)日:2006-08-31
申请号:US11322960
申请日:2005-12-30
申请人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号: A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译: 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法,例如进行心胸外科手术的患者例如围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术,特别是当此类手术涉及体外循环,如体外循环时。
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公开(公告)号:US20080064637A1
公开(公告)日:2008-03-13
申请号:US11796272
申请日:2007-04-27
申请人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人: Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号: A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译: 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法,例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术,特别是当此类手术涉及体外循环,如体外循环时。
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公开(公告)号:US20090062195A1
公开(公告)日:2009-03-05
申请号:US11929876
申请日:2007-10-30
申请人: Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人: Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
CPC分类号: A61K38/57
摘要: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译: 描述了用于预防或减少患者中局部缺血,例如脑缺血和/或再灌注损伤(例如与脑缺血相关的再灌注损伤)的方法。
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公开(公告)号:US07704949B2
公开(公告)日:2010-04-27
申请号:US11466979
申请日:2006-08-24
申请人: Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia Simoni , Luigi Bergamaschini
发明人: Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia Simoni , Luigi Bergamaschini
CPC分类号: A61K38/57
摘要: Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译: 描述了用于预防或减少患者中局部缺血,例如脑缺血和/或再灌注损伤(例如与脑缺血相关的再灌注损伤)的方法。
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公开(公告)号:US20080152656A1
公开(公告)日:2008-06-26
申请号:US11931635
申请日:2007-10-31
IPC分类号: A61K39/395 , A61P43/00
CPC分类号: A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译: 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法,例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术,特别是当此类手术涉及体外循环,如体外循环时。
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公开(公告)号:US07064107B2
公开(公告)日:2006-06-20
申请号:US10456986
申请日:2003-06-06
CPC分类号: A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g., coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译: 描述了用于预防或减少患者中的缺血和/或全身炎症反应的方法,例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应,例如冠状动脉旁路移植术和其他外科手术,特别是当这样 手术涉及体外循环,如体外循环。
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