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公开(公告)号：US20050164928A1
公开(公告)日：2005-07-28
申请号：US10953902
申请日：2004-09-27
申请人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
发明人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20070049522A1
公开(公告)日：2007-03-01
申请号：US11466979
申请日：2006-08-24
申请人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
发明人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams , Maria De Simoni , Luigi Bergamaschini
IPC分类号： A61K38/55
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20080076712A1
公开(公告)日：2008-03-27
申请号：US11929729
申请日：2007-10-30
申请人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
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公开(公告)号：US20070249807A1
公开(公告)日：2007-10-25
申请号：US11323261
申请日：2005-12-30
申请人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号： C07K14/8114 , C07K14/8121
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US20060194727A1
公开(公告)日：2006-08-31
申请号：US11322960
申请日：2005-12-30
申请人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者例如围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US20080064637A1
公开(公告)日：2008-03-13
申请号：US11796272
申请日：2007-04-27
申请人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
发明人： Robert Ladner , Arthur Ley , Shirish Hirani , Anthony Williams
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US20090117130A1
公开(公告)日：2009-05-07
申请号：US11930897
申请日：2007-10-31
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
IPC分类号： A61K39/395 , A61P25/00
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20080139473A1
公开(公告)日：2008-06-12
申请号：US11929822
申请日：2007-10-30
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
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公开(公告)号：US07704949B2
公开(公告)日：2010-04-27
申请号：US11466979
申请日：2006-08-24
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20090062195A1
公开(公告)日：2009-03-05
申请号：US11929876
申请日：2007-10-30
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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