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公开(公告)号：US09750761B2
公开(公告)日：2017-09-05
申请号：US14718933
申请日：2015-05-21
IPC分类号： A01N35/00 , A61K31/11 , A61K31/713 , A61K31/404 , A61K45/06 , A61K31/12 , C12N15/113
CPC分类号： A61K31/713 , A61K31/12 , A61K31/404 , A61K45/06 , C12N15/1137 , C12N2310/14 , C12N2320/31 , C12Y101/01027 , C12Y101/01028 , A61K2300/00
摘要： One aspect of the disclosure relates to methods of treating a fibrotic condition in an individual. The methods include administering to an individual having a fibrotic condition an effective amount of a lactic dehydrogenase (LDH) inhibitor, wherein the fibrotic condition involves an internal organ or tissue, or ocular tissue, and said administering is effective to treat the fibrotic condition. Methods of administration and pharmaceutical compositions and systems for practicing such methods are also disclosed.
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2.发明申请公开(公告)号：US20150335674A1
公开(公告)日：2015-11-26
申请号：US14718933
申请日：2015-05-21
IPC分类号： A61K31/713 , C12N15/113 , A61K31/12 , A61K31/404 , A61K45/06
CPC分类号： A61K31/713 , A61K31/12 , A61K31/404 , A61K45/06 , C12N15/1137 , C12N2310/14 , C12N2320/31 , C12Y101/01027 , C12Y101/01028 , A61K2300/00
摘要： One aspect of the disclosure relates to methods of treating a fibrotic condition in an individual. The methods include administering to an individual having a fibrotic condition an effective amount of a lactic dehydrogenase (LDH) inhibitor, wherein the fibrotic condition involves an internal organ or tissue, or ocular tissue, and said administering is effective to treat the fibrotic condition. Methods of administration and pharmaceutical compositions and systems for practicing such methods are also disclosed.
摘要翻译： 本公开的一个方面涉及治疗个体中的纤维化病症的方法。 所述方法包括向具有纤维化病症的个体施用有效量的乳酸脱氢酶（LDH）抑制剂，其中所述纤维化病症涉及内部器官或组织或眼组织，并且所述施用对于治疗所述纤维化病症是有效的。 还公开了施用方法和用于实施这些方法的药物组合物和系统。
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