公开(公告)号：US5421812A

公开(公告)日：1995-06-06

申请号：US845677

申请日：1992-03-04

申请人： Robert W. Langley ,  Michael E. Schwab

发明人： Robert W. Langley ,  Michael E. Schwab

IPC分类号： A61M1/30 ,  A61M1/34 ,  A61M1/36 ,  A61M1/00

CPC分类号： A61M1/3672 ,  A61M1/303 ,  A61M1/30 ,  A61M1/34 ,  A61M1/3693

摘要： A method and apparatus for determining, controlling or establishing the level of a constituent such as anticoagulant in a body fluid such as blood in a procedure for processing the fluid. The anticoagulant flow rate from an anticoagulant reservoir, the blood flow rate, the flow rate of collected fluid and the flow rate of replacement fluid are monitored, and an anticoagulant flow balance is established whereby the flow of anticoagulant into the donor or patient will be equal to the flow rate of anticoagulant out of the anticoagulant reservoir, plus the flow rate of anticoagulant from the donor or patient, plus the flow rate of anticoagulant in the replacement fluid, minus the flow rate of anticoagulant in the collect fluid. The flow rate of anticoagulant from the donor or patient can be determined based on the anticoagulant metabolic half-life, the volume of the donor's or patient's blood, and the amount and time of infusion of anticoagulant into the donor or patient.

摘要翻译： 一种用于在用于处理流体的过程中用于确定，控制或建立诸如血液中的体液中的抗凝血剂等成分的水平的方法和装置。 监测来自抗凝血储存器的抗凝血流量，血流速度，收集流体的流速和置换液的流速，建立抗凝血流量平衡，由此抗体凝血剂进入供体或患者的流量将相等 抗凝血剂储存器中抗凝血剂的流量加上来自供体或患者的抗凝血剂的流量加上置换液中抗凝血剂的流量减去收集液中抗凝血剂的流速。 来自供体或患者的抗凝血剂的流速可以基于抗凝剂代谢半衰期，供体或患者血液的体积以及将抗凝剂输入供体或患者的量和时间来确定。