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公开(公告)号：US20100286223A1
公开(公告)日：2010-11-11
申请号：US12840425
申请日：2010-07-21
CPC分类号： C07D487/04 , C07D491/04 , C07D495/04
摘要： Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer.
摘要翻译： 本说明书中定义的式（I）的双 - 吡唑化合物及其药学上可接受的盐，其制备方法，包含其中的多个组合文库及其药物组合物，本文公开了本发明的化合物， 在治疗中，作为蛋白激酶抑制剂，例如用于治疗癌症。
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公开(公告)号：US20090233813A1
公开(公告)日：2009-09-17
申请号：US12472513
申请日：2009-05-27
CPC分类号： C07D487/04 , C07D491/04 , C07D495/04
摘要： Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer.
摘要翻译： 本说明书中定义的式（I）的双 - 吡唑化合物及其药学上可接受的盐，其制备方法，包含其中的多个组合文库及其药物组合物，本文公开了本发明的化合物， 在治疗中，作为蛋白激酶抑制剂，例如用于治疗癌症。
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公开(公告)号：US20060160874A1
公开(公告)日：2006-07-20
申请号：US11037986
申请日：2005-01-18
IPC分类号： A61K31/4162 , C07D487/02 , C07D491/02 , C07D498/02
CPC分类号： C07D491/04 , C07D495/04
摘要： Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
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公开(公告)号：US20060122249A1
公开(公告)日：2006-06-08
申请号：US10522250
申请日：2003-07-11
IPC分类号： A61K31/4162 , C07D487/02
CPC分类号： C07D487/04 , C07D491/04 , C07D495/04
摘要： Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer.
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